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01518

Ginsenoside Rd

analytical standard

Synonim(y):

(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside, Gypenoside VIII

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Gabaryty przesyłkiSKUDostępnośćCena netto
10 mg
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1200,00 zł

Informacje o tej pozycji

Wzór empiryczny (zapis Hilla):
C48H82O18
Numer CAS:
Masa cząsteczkowa:
947.15
NACRES:
NA.24
UNSPSC Code:
85151701
EC Number:
258-118-5

1200,00 zł


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grade

analytical standard

Quality Segment

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

C\C(C)=C/CC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]2CC[C@]3(C)[C@@H]2[C@H](O)C[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)[C@@H]5CC[C@@]34C

InChI

1S/C48H82O18/c1-21(2)15-22(3)17-48(8,66-43-40(60)37(57)34(54)28(19-50)62-43)24-11-13-47(7)23-9-10-30-45(4,5)31(12-14-46(30,6)25(23)16-26(52)32(24)47)64-44-41(38(58)35(55)29(20-51)63-44)65-42-39(59)36(56)33(53)27(18-49)61-42/h15,22-44,49-60H,9-14,16-20H2,1-8H3/t22?,23?,24-,25?,26-,27+,28+,29+,30?,31?,32+,33+,34+,35+,36-,37-,38-,39+,40+,41+,42-,43-,44-,46+,47+,48-/m0/s1

InChI key

IRBVCFDYIGGFFY-ADSMOORZSA-N

General description

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng. Ginsenoside Rd is the main active component of ginsenosides, having the ability to inhibit Ca2+ influx through receptors and store-operated Ca2+ channel. From neural stem cells, it is seen to enhance astrocyte differentiation. It also reduces the 3-nitropropionic acid-induced motor impairment and cell loss in stratum. It constitutes to one of the major ingredient in total saponin content from Panax notoginseng.[1]

Application

It was used as reference standard in UPLC/TOF-MS analysis of human plasma to determine Ginsenoside metabolites.[2]

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

This compound is commonly found in plants of the genus: panax
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Ta pozycja
03000590PHL89211PHL80462
Ginsenoside Re primary reference standard

03000590

Ginsenoside Re

Ginsenoside Rd phyproof® Reference Substance

PHL89211

Ginsenoside Rd

Ginsenoside Ro phyproof® Reference Substance

PHL80462

Ginsenoside Ro

grade

analytical standard

grade

primary reference standard

grade

primary reference standard

grade

primary reference standard

application(s)

food and beverages

application(s)

food and beverages

application(s)

food and beverages

application(s)

-

assay

≥95.0% (HPLC)

assay

-

assay

≥90.0% (HPLC)

assay

≥90.0% (HPLC)

format

neat

format

-

format

neat

format

-

shelf life

limited shelf life, expiry date on the label

shelf life

limited shelf life, expiry date on the label

shelf life

-

shelf life

-

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

storage temp.

2-8°C


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Klasa składowania

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Produkty

Optimize HPLC method for ginsenoside separation using a mixture, applying it to American Ginseng root, with conditions and chromatograms shown.


X Liu et al.
European journal of neurology, 19(6), 855-863 (2012-01-12)
Ginsenoside-Rd is a receptor-operated calcium channel antagonist and has shown promise as a neuroprotectant in our phase II study. As an extended work, we sought to confirm its efficacy and safety of Ginsenoside-Rd in patients with acute ischaemic stroke. We
Li Wang et al.
The Journal of surgical research, 176(1), 267-274 (2011-08-30)
Organ transplantation is a life-saving procedure for patients with organ failure. However, the side effects of long-term application of classic immunosuppressant remain major obstacles for successful transplantation. Therefore, new and safe immunosuppressive drugs against acute and chronic rejection are eagerly
Jie Li et al.
European journal of pharmacology, 652(1-3), 104-110 (2010-12-03)
Recently, it was revealed that the dysfunction of transmembrane Ca(2+) transport, results in an increase in intracellular Ca(2+)[Ca(2+)](i), which is involved in the process of atherosclerosis. We previously demonstrated that ginsenoside-Rd, a purified component from panax notoginseng, is a voltage-independent



Numer pozycji handlu globalnego

SKUNUMER GTIN
W234702-SAMPLE04061838191472
W234702-100G04061838093257
W234702-25G04061838079930
W234702-1KG04061838180018
C104507-5G04061836689797
C104507-25G04061836696115
01518-10MG04061834088103

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