MAB3560-C
Anti-8-Oxoguanine, clone 483.15 Antibody (Ascites Free)
clone 483.15, from mouse
Synonim(y):
8-Oxoguanine
Wybierz wielkość
| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 100 μg | Dostępne do wysyłki DZISIAJzKuehne + Nagel Sp. z o.o. | 2600,00 zł |
Informacje o tej pozycji
biological source
mouse
Quality Segment
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
483.15, monoclonal
species reactivity
rat, human, monkey, bovine, mouse
species reactivity (predicted by homology)
all
technique(s)
ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry: suitable
isotype
IgMκ
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... OGG1(4968)
General description
Immunogen
Application
Immunohistochemistry Analysis: A representative lot detected increased nuclear 8-oxoguanine (8-oxoG) immunoreactivity in paraffin-embedded coronal hippocampus sections from mice induced to express mutated mitochondrial isoform Uracil–DNA glycosylase by fluorescent immunohistochemistry (Lauritzen, K.H., et al. (2011). DNA Repair (Amst). 10(6):639-653).
Immunohistochemistry Analysis: A representative lot detected significantly increased nuclear 8-oxoguanine (8-oxoG) immunoreactivity in ovaries excised from neonatal mice upon exposure to ovotoxic agent 4-vinylcyclohexene diepoxide (VCD), methoxychlor (MXC), or menadione (MEN) in culture by fluorescent immunohistochemistry (Sobinoff, A.P., et al. (2010). Toxicol. Sci. 118(2):653-666).
Immunocytochemistry Analysis: A representative lot detected significantly increased 8-oxoguanine (8-oxoG) immunoreactivity in RINm5F rat insulinoma cells upon IL-1beta or ROS-inducer menadione treatment (Mehmeti, I., et al. (2011). Biochim. Biophys. Acta. 1813(10):1827-1835).
Immunocytochemistry Analysis: A representative lot detected significantly increased nuclear 8-oxoguanine (8-oxoG) immunoreactivity in AC16 human cardiomyocytes upon infection by the hemoflagellate protozoan parasite Trypanosoma cruzi (Ba, X., et al. (2010). J. Biol. Chem. 285(15):11596-11606).
Immunocytochemistry Analysis: Representative lots detected nutrient-deprivation-induced enhancement of nuclear 8-oxoguanine (8-oxoG) immunoreactivity in HeLa and COS-7 cells by fluorescent immunocytochemistry (Conlon, K.A., et al. (2003). DNA Repair (Amst). 2(12):1337-1352; Conlon, K.A., et al. (2000). J. Histotechnol. 23(1):37-44).
ELISA Analysis: Specificity of a representative lot against 8-oxoguanine was confirmed by competitive ELISA. Competition by dGMP, dAMP, dCMP or TMP was only observed when the concentrations were increased to the millimolar range.
Biochem/physiol Actions
Physical form
Analysis Note
Immunocytochemistry Analysis: A 1:50 dilution of this antibody detected 8-Oxoguanine in HeLa cells.
Other Notes
1 of 1
Ta pozycja | |||
|---|---|---|---|
| biological source mouse | biological source mouse | biological source goat | biological source mouse |
| Gene Information human ... OGG1(4968) | Gene Information human ... OGG1(4968) | Gene Information - | Gene Information - |
| antibody form purified immunoglobulin | antibody form ascites fluid | antibody form serum | antibody form purified antibody |
| clone 483.15, monoclonal | clone 483.15, monoclonal | clone polyclonal | clone NO2-52, monoclonal |
| species reactivity rat, human, monkey, bovine, mouse | species reactivity monkey, human, primate | species reactivity human | species reactivity mouse, rat |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
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Klasa składowania
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| MAB3560-C | 04055977296419 |