48-655MAG

MILLIPLEX^® Protein Translation Signaling Panel

Premixed Protein Translation 6-Plex Cell Signaling Panel

• Synonim(y): 4E-BP1 phosphorylation, eIF2α assay, mTOR pathway assay, p70S6K multiplex, phospho-translation markers, protein synthesis panel, translation regulation assay, translational signaling multiplex
• NACRES: NA.47
• UNSPSC Code: 12161503

Właściwości

• Nazwa produktu: MILLIPLEX^® Protein Translation Signaling Panel,
• Quality Segment: 200
• description: Premixed Protein Translation 6-Plex Cell Signaling Panel
• species reactivity: human, rat, mouse
• packaging: pkg of 1 ea
• manufacturer/tradename: Milliplex^®
• technique(s): multiplexing: suitable
• input: cell lysate
• detection method: fluorometric (Luminex^® xMAP^® technology)
• shipped in: wet ice
• storage temp.: 2-8°C

Opis

General description

This panel targets phosphorylated proteins involved in the regulation of protein synthesis. It includes p70S6K (pT412), 4E-BP1 (pT37/46), eIF2α (pS51), eIF4E (pS209), mTOR (pS2448), and RPS6 (pS235/236). These proteins are downstream effectors of the mTOR pathway and play critical roles in translation initiation, cell growth, and metabolism. The panel supports studies in cancer, metabolic disorders, and cellular stress responses.

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 6 analytes in human, mouse, or rat cell lysate samples.

Analytes Included: p70S6K (Phospho-Thr412), 4E-BP1 (Phospho-Thr37/46), eIF2α (Phospho-Ser51), eIF4E (Phospho-Ser209), mTOR (Phospho-Ser2448), RPS6 (Phospho-Ser235/236)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate^™ Control Assays).

Features and Benefits

• Simultaneously detect 6 phosphorylated proteins involved in protein synthesis regulation
• Includes p70S6K, 4E-BP1, eIF2α, eIF4E, mTOR, and RPS6
• Magnetic bead-based format ensures reproducibility and efficient processing
• Compatible with cell lysates from cancer, metabolic, and stress response studies
• Ideal for translational control, oncology, and mTOR pathway research
• Fast, convenient alternative to Western Blotting and immunoprecipitation procedures

Legal Information

Luminex is a registered trademark of Luminex Corp

MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• Klasa składowania: 10 - Combustible liquids
• wgk: WGK 3
• hcodes: H302,H315,H318,H410,EUH430
• pcodes: P201 - P202 - P273 - P280 - P305 + P351 + P338 - P391 - P405 - P501
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2