48-614MAG

MILLIPLEX^® TGFβ Signaling Pathway Panel

Premixed TGFβ 6-Plex Cell Signaling Panel

• Synonim(y): Cell Signaling Assay, Luminex^® TGFβ Cell Signaling Assay, Millipore TGFβ Cell Signaling Assay, TGFβ Signal Transduction Assay, SMAD signaling, TGFβ ELISA, TGFβ assay, TGFβ pathway multiplex, TGFβ phospho assay, TGF-beta multiplex, fibrosis signaling panel, transforming growth factor beta
• NACRES: NA.47
• UNSPSC Code: 12161503

Właściwości

• Nazwa produktu: MILLIPLEX^® TGFβ Signaling Pathway Panel,
• Quality Segment: 200
• description: Premixed TGFβ 6-Plex Cell Signaling Panel
• species reactivity: human
• packaging: pkg of 1 ea
• manufacturer/tradename: Milliplex^®
• technique(s): multiplexing: suitable
• input: cell lysate
• detection method: fluorometric (Luminex^® xMAP^® technology)
• shipped in: wet ice
• storage temp.: 2-8°C

Opis

General description

This panel targets phosphorylated proteins in the TGFβ signaling pathway, which regulates cell growth, differentiation, and immune responses. SMAD2 (pS465/pS467) and SMAD3 (pS423/pS425) are direct mediators of TGFβ receptor activation. TAK1 (pS412), p38 (pT180/pY182), ERK1/2 (pT185/pY187), and JNK (pT183/pY185) represent downstream MAPKs involved in inflammation, fibrosis, and cancer progression.

Application

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 6 analytes in cell lysate samples.

Analytes Included: SMAD2 (Phospho-Ser465/467), SMAD3 (Phospho-Ser423/425), TAK1 (Phospho-Ser412), p38 (Phospho-Thr180/Tyr182), ERK1/2 (Phospho-Thr185/Tyr187), JNK (Phospho-Thr183/Tyr185)

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, buffer compatibility, lysate control, and recommended loading control (MAPmate^™ Control Assays).

Features and Benefits

• Simultaneously detect 6 phosphorylated proteins in the TGFβ signaling pathway
• Includes SMAD2, SMAD3, TAK1, p38, ERK1/2, and JNK
• Magnetic bead-based format ensures reproducibility and efficient processing
• Compatible with cell lysates from fibrosis, inflammation, and cancer models
• Ideal for fibrosis, immunology, and cell signaling research
• Fast, convenient alternative to Western Blotting and immunoprecipitation procedures

Legal Information

Luminex is a registered trademark of Luminex Corporation

MAPMATE is a trademark of Merck KGaA, Darmstadt, Germany

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS05,GHS07,GHS09
• signalword: Danger
• Klasa składowania: 10 - Combustible liquids
• wgk: WGK 3
• hcodes: H302 + H312,H315,H318,H410,EUH430
• pcodes: P201 - P202 - P273 - P280 - P305 + P351 + P338 - P391 - P405 - P501
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2