420307

Kallikrein, Human Plasma

Native Kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an inactive precursor, prokallikrein.

• Synonim(y): Kallikrein, Human Plasma, Kininogenin, Kininogenase
• Numer CAS: 9001-01-8
• Numer WE: 3.4.21.34 (BRENDA, IUBMB)
• UNSPSC Code: 12352202
• NACRES: NA.77
• MDL number: MFCD00131428
• Specific activity: ≥15 units/mg protein
• Assay: ≥95% (SDS-PAGE)
• Biological source: human plasma

Właściwości

• biological source: human plasma
• Quality Segment: 100
• description: Merck USA index - 14, 5279
• assay: ≥95% (SDS-PAGE)
• form: liquid
• specific activity: ≥15 units/mg protein
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, avoid repeated freeze/thaw cycles
• storage temp.: −20°C

Opis

General description

Native Kallikrein from human plasma. A serine protease that releases bradykinin from kininogen. Present in the plasma as an inactive precursor, prokallikrein.

Packaging

Please refer to vial label for lot-specific concentration.

Physical form

In NaCl and Tris-HCl buffer.

Preparation Note

Following initial thaw, aliquot and freeze (-20°C).

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Other Notes

One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol D-Pro-Phe-Arg-pNA per min at 25°C, pH 8.0.

Pu, X., et al. 1994. Biochim. Biophys. Acta 1208, 338.
Nagase, H. and Barrett, A.J. 1981. Biochem. J.193, 187.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Toxicity: Harmful (C)

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable