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385931

Sigma-Aldrich

Hyaluronidase, Bovine Testes

Synonim(y):

Hyaluronidase, Bovine Testes

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Wybierz wielkość

25 KU
1660,00 zł

1660,00 zł


Przewidywany termin wysyłki22 kwietnia 2025Szczegóły



Wybierz wielkość

Zmień widok
25 KU
1660,00 zł

About This Item

Numer CAS:
Numer EC enzymu:
Numer MDL:
Kod UNSPSC:
12352202
NACRES:
NA.54

1660,00 zł


Przewidywany termin wysyłki22 kwietnia 2025Szczegóły


białko sprzężone

conjugate (Glucosaminoglycan)

Poziom jakości

opis

Merck USA index - 14, 4758

Formularz

lyophilized

aktywność właściwa

≥2500 units/mg dry wt.

producent / nazwa handlowa

Calbiochem®

warunki przechowywania

OK to freeze

Warunki transportu

ambient

temp. przechowywania

−20°C

Opis ogólny

Native hyaluronidase from bovine testes. Catalyzes the hydrolysis of 1,4 linkages between N-acetylhexosamine and D-glucuronate residues in chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, and hyaluronic acid.
Native hyaluronidase from bovine testes. Hyaluronic acid degrading endoglycosidase that catalyzes the hydrolysis of 1,4 linkages between N-acetylhexosamine and D-glucuronate residues in chondroitin, chondroitin-4-sulfate, chondroitin-6-sulfate, and hyaluronic acid.
Note: 1 KU = 1000 units.

Ostrzeżenie

Toxicity: Standard Handling (A)

Definicja jednostki

One unit is defined as the amount of enzyme that will cause the same turbidity reduction as 1.0 unit of International Standard preparation.

Rekonstytucja

Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 1 week at 4°C.
Reconstitute in 20 mM sodium phosphate, pH 6.9, 0.45% NaCl, and 0.01% BSA.

Inne uwagi

Lokeshwar, V.B., et al. 2002. J. Biol. Chem.277, 33654.
Humphrey, I.H. 1957. Bull. WHO16, 291.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Ta strona może zawierać tekst przetłumaczony maszynowo.

Piktogramy

Health hazard

Hasło ostrzegawcze

Danger

Zwroty wskazujące rodzaj zagrożenia

Zwroty wskazujące środki ostrożności

Klasyfikacja zagrożeń

Resp. Sens. 1

Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

J H HUMPHREY
Bulletin of the World Health Organization, 16(2), 291-294 (1957-01-01)
The International Standard for Hyaluronidase is derived from a blend of four batches of bovine testicular hyaluronidase which had been purified so as to contain approximately 400 units per milligram. The material was mixed with beta-lactose, and lyophilized. Tablets were
Vinata B Lokeshwar et al.
The Journal of biological chemistry, 277(37), 33654-33663 (2002-06-27)
Hyaluronidase is a hyaluronic acid-degrading endoglycosidase that is present in many toxins and the levels of which are elevated in cancer. Increased concentration of HYAL1-type hyaluronidase correlates with tumor progression and is a marker for grade (G) 2 or 3

Produkty

Explore the role of hyaluronan, hyaluronic acid structure, hyaluronan synthesis & degradation, and more. Find GAGs, hydrogels, and scaffold kits.

Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.

Dowiedz się więcej o glikozoaminoglikanach i proteoglikanach, w tym o strukturze glikozoaminoglikanów (GAG), różnych typach GAG i ich funkcjach.

Questions

1–3 of 3 Questions  
  1. I am doing experiments on hyaluronidase activity and I would like information on how the reconstituted enzyme performs after being frozen and thawed at both -20C and -80C

    1 answer
    1. It is recommended to reconstitute this product in 20 mM sodium phosphate, pH 6.9, 0.45% NaCl, and 0.01% BSA at 5 mg/mL. Following reconstitution, store at 2 - 8°C up to 1 week. Stock solutions may be stored in working aliquots at -20°C for several months. Avoid repeated freeze/thaw cycles.

      Helpful?

  2. What is molecular weight of this product (in kDa)?

    1 answer
    1. The molecular weight is approximately 61 kDa. This information may be found on the Certificate of Analysis.

      Helpful?

  3. We have a bottle of Hyaluronidase, Bovine Testes in our lab and need to know if it has an expiration date. The only date on the bottle is the received date written by one of the techs. If it is stored properly in the freezer what is the expiration date?

    1 answer
    1. This product is not assigned an expiration date or recommended retest date. Customers should routinely inspect products with no expiration date or recommended retest date to ensure they perform as expected. These products are also subject to a one-year warranty from the date of shipment. For more information, you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

      To discuss further, we kindly ask you to navigate to the link https://www.sigmaaldrich.com/techservice, click on "Report Product Issues" under the Products Section with all the required information, including the lot number, so that a member of our team can reach out to you to assist further. Thank you.

      Helpful?

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