382129
HIV Reverse Transcriptase, Recombinant, E. coli
liquid, ≥5,000 units/mg protein, Nuclease-free
Synonim(y):
HIV RT
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About This Item
Kod UNSPSC:
12352202
NACRES:
NA.54
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rekombinowane
expressed in E. coli
Poziom jakości
Postać
liquid
aktywność właściwa
≥10,000 units/mL
≥5,000 units/mg protein
producent / nazwa handlowa
Calbiochem®
warunki przechowywania
OK to freeze
metody
molecular cloning: suitable
obecność zanieczyszczeń
Nuclease-free
Warunki transportu
wet ice
temp. przechowywania
−20°C
Opis ogólny
Recombinant HIV reverse transcriptase expressed in E. coli. Catalyzes error-prone synthesis on DNA and RNA templates. Provides an excellent target for evaluating antiviral agents.
Zastosowanie
HIV Reverse Transcriptase, Recombinant, E.coli has been used as a standard in reverse transcriptase activity assay.
Opakowanie
Please refer to vial label for lot-specific concentration.
Ostrzeżenie
Toxicity: Standard Handling (A)
Definicja jednostki
One unit is defined as the amount of enzyme that will incorporate 1.0 nmol of labeled dTTP into acid-insoluble material in 20 min at 37°C, pH 8.3.
Postać fizyczna
In 10 mM potassium phosphate, 1 mM DTT, 20% glycerol, pH 7.4.
Rekonstytucja
Following initial thaw, aliquot and freeze (-20°C).
Informacje prawne
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 1
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
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Infection of rhesus macaques with simian-human immunodeficiency viruses (SHIVs) is the preferred model system for vaccine development because SHIVs encode human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins (Envs)-a key target of HIV-1 neutralizing antibodies. Since the goal of vaccines
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Reed JC, et al.
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Conformation of HIV-1 Envelope governs rhesus CD4 usage and simian-human immunodeficiency virus replication
Vilmen G, et al.
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Bo Meng et al.
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Jonathan C Reed et al.
Journal of virology, 95(3) (2020-11-06)
Given the projected increase in multidrug-resistant HIV-1, there is an urgent need for development of antiretrovirals that act on virus life cycle stages not targeted by drugs currently in use. Host-targeting compounds are of particular interest because they can offer
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