324744-M

Elastase Inhibitor II

The Elastase Inhibitor II controls the biological activity of Elastase. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

• Synonim(y): Elastase Inhibitor II, HNE Inhibitor, MeOSuc-AAPA-CMK, MSACK
• Wzór empiryczny (zapis Hilla): C₂₀H₃₁ClN₄O₇
• Masa cząsteczkowa: 474.94
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥99% (TLC)
• Form: lyophilized solid
• Storage condition: OK to freeze, desiccated

Właściwości

• Quality Segment: 100
• assay: ≥99% (TLC)
• form: lyophilized solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated
• color: white
• solubility: DMSO: 10 mg/mL, methanol: soluble
• storage temp.: −20°C

Opis

General description

A potent inhibitor of human neutrophil elastase (HNE).The inhibition results from cross-linking of catalytic residues His⁵⁷ and Ser¹⁹⁵ in the HNE in the presence of this inhibitor.

A potent irreversible inhibitor of human neutrophil elastase (HNE). Inhibition results from cross-linking of the catalytic residues His⁵⁷ and Ser¹⁹⁵.

Biochem/physiol Actions

Primary Target
Human neutrophil elastase (HNE)

Preparation Note

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

Other Notes

MeOSuc-Ala-Ala-Pro-Ala-CMK

Navia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
Williams, H.R., et al. 1987. J. Biol. Chem.262, 17178.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable