322133
DSP, Water-Soluble
Synonim(y):
3,3-Dithio- bis-(sulfosuccinimidyl)propionate, DTSSP, Sulfo-DSP, 3,3-Dithio-bis-(sulfosuccinimidyl)propionate, DTSSP, Sulfo-DSP
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 100 mg | Sprawdź dostępność w koszyku | 1290,00 zł |
Informacje o tej pozycji
NACRES:
NA.24
UNSPSC Code:
41116133
1290,00 zł
Sprawdź dostępność w koszyku
Pomoc techniczna
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Pozwól nam pomócassay
≥94% (HPLC)
Quality Level
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated
color
off-white to light tan
solubility
water: 6 mg/mL
shipped in
ambient
storage temp.
2-8°C
General description
Bifunctional cross-linker. The disulfide bond can be cleaved with 1% NaBH4, 50 mM DTT, or 100 mM β-mercaptoethanol. Has been used to immobilize proteins on supports containing amino groups. Chemical crosslinkers are used to covalently modify proteins for studying ligand receptor interactions, conformational changes in tertiary structure, or for protein labeling. Crosslinkers are divided into homobifunctional crosslinkers, containing two identical reactive groups, or heterobifunctional crosslinkers, containing two different reactive groups. Water-soluble cross-linking reagents help to avoid the use of organic solvents such as dimethylformamide (DMF) and dimethylsulfoxide (DMSO) when preparing bioconjugates.
Preparation Note
Following each use, purge the original vial with inert gas and refrigerate (4°C). Unstable in aqueous solution; reconstitute just prior to use. Alternatively, the solid DSP can be added directly to the sample to minimize hydrolysis. Hydrolysis is more pronounced in dilute protein solutions and can, therefore, be minimized by using more concentrated protein solutions (>5 mg/ml). For storage of stock solutions, reconstitute in anhydrous DMSO.
Other Notes
Howard, A.D., et al. 1985. J. Biol. Chem.260, 10833.
Lee, W.T., and Conrad, D.H. 1985. J. Immunol.134, 518.
D′Souza, S.E., et al. 1988. J. Biol. Chem.263, 3943.
Yamada, H., et al. 1981. Biochem.20, 4836.
Annunziato, M.E., et al. 1993. Bioconjugate Chem.4, 212.
Lee, W.T., and Conrad, D.H. 1985. J. Immunol.134, 518.
D′Souza, S.E., et al. 1988. J. Biol. Chem.263, 3943.
Yamada, H., et al. 1981. Biochem.20, 4836.
Annunziato, M.E., et al. 1993. Bioconjugate Chem.4, 212.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
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Ta pozycja | |||
|---|---|---|---|
| manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename - | manufacturer/tradename - |
| form solid | form powder | form powder | form powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C | storage temp. −20°C |
| assay ≥94% (HPLC) | assay ≥80% | assay ≥90% | assay - |
| storage condition OK to freeze, desiccated | storage condition desiccated | storage condition desiccated | storage condition - |
| shipped in ambient | shipped in ambient | shipped in ambient | shipped in - |
![Sulfo-LC-SPDP (sulfosuccinimidyl 6-[3′-(2-pyridyldithio)propionamido]hexanoate)](/deepweb/assets/sigmaaldrich/product/structures/266/633/e2a263be-4bd3-4fcf-89c4-75b5e2bd829c/640/e2a263be-4bd3-4fcf-89c4-75b5e2bd829c.png)
Klasa składowania
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| 322133-100MG | 04055977216318 |