The substance dissolves in DMSO at concentrations of up to 8 mg/ml.
317240
Metformin
≥97% (titration), solid, AMPK signaling activator, Calbiochem®
Synonim(y):
Metformin, 1,1-Dimethylbiguanide, Hydrochloride, AMPK Signaling Activator VII
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
|---|---|---|---|
| 5 g | Przewidywany termin wysyłki24 marca 2026zKuehne + Nagel Sp. z o.o. | 661,00 zł |
Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C4H11N5 · xHCl
Numer CAS:
Masa cząsteczkowa:
129.16 (free base basis)
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥97% (titration)
Form:
solid
Quality level:
Storage condition:
OK to freeze, desiccated (hygroscopic)
Pomoc techniczna
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Pozwól nam pomócNazwa produktu
Metformin, An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia.
Quality Level
description
Merck USA index - 14, 5938
assay
≥97% (titration)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
water: 50 mg/mL
shipped in
ambient
Powiązane kategorie
1 of 1
Ta pozycja | |||
|---|---|---|---|
| form solid | form - | form - | form - |
| manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename EDQM | manufacturer/tradename USP |
| assay ≥97% (titration) | assay - | assay - | assay - |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level - |
| storage condition OK to freeze, desiccated (hygroscopic) | storage condition - | storage condition - | storage condition - |
| solubility water: 50 mg/mL | solubility - | solubility - | solubility - |
General description
An anti-hyperglycemic agent that acts by lowering the hepatic output of glucose. Does not stimulate insulin secretion, promote weight gain, or cause hypoglycemia. Reported to stimulate AMP-activated protein kinase (AMPK), leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation.
An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia. Reported to stimulate AMP-activated protein kinase (AMPK) leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation.
Biochem/physiol Actions
Cell permeable: no
Primary Target
AMP-activated protein kinase (AMPK)
AMP-activated protein kinase (AMPK)
Product does not compete with ATP.
Reversible: no
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Cleasby, M.E., et al. 2004. Diabetes53, 3258.
Klein, J., et al. 2004. J. Endocrinol.183, 299.
Zhou, G., et al. 2001. J. Clin. Invest.108, 1167.
Lin, H.Z., et al. 2000. Nat. Med.6, 998.
Klein, J., et al. 2004. J. Endocrinol.183, 299.
Zhou, G., et al. 2001. J. Clin. Invest.108, 1167.
Lin, H.Z., et al. 2000. Nat. Med.6, 998.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
Ta strona może zawierać tekst przetłumaczony maszynowo.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Klasa składowania
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certyfikaty analizy (CoA)
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Numer pozycji handlu globalnego
| SKU | NUMER GTIN |
|---|---|
| 317240-5GM | 04055977216196 |
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What is the solubility of Metformin (Cat#317240) in DMSO?
1 answer-
Helpful?
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is metformin accociated with paracitic worms?
1 answer-
There have been studies published regarding the efficacy of Metformin against various parasites. Please see the link below to review one such study of Echinococcisis. Note that this product is intended for research use only and is not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321462/Helpful?
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