288500-M
DL-α-Difluoromethylornithine, Hydrochloride
A cell-permeable, anticancer agent that acts as a specific and irreversible inhibitor of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis.
Synonim(y):
DL-α-Difluoromethylornithine, Hydrochloride, DFMO, Eflornithine, RMI-71782
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| Gabaryty przesyłki | SKU | Dostępność | Cena netto |
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Informacje o tej pozycji
Quality Level
description
Merck USA index - 14, 3522
assay
≥99% (HPLC)
form
powder
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, desiccated (hygroscopic)
color
white
solubility
water: 1 mg/mL, methanol: 25 mg/mL
storage temp.
10-30°C
SMILES string
FC(F)C(N)(CCCN)C(=O)O.[Cl-].O.[H+]
InChI
1S/C6H12F2N2O2.ClH.H2O/c7-4(8)6(10,5(11)12)2-1-3-9;;/h4H,1-3,9-10H2,(H,11,12);1H;1H2
InChI key
FJPAMFNRCFEGSD-UHFFFAOYSA-N
General description
Biochem/physiol Actions
ODC
Preparation Note
Other Notes
Feuerstein, B.G., et al. 1992. Cancer Res. 52, 6782.
Takigawa, M., et al. 1990. Cancer Res.50, 4131.
Weeks, C.E., et al. 1982. Proc. Natl. Acad. Sci. USA 79, 6028.
Danzin, C., et al. 1979. Life Sci. 24, 519.
Legal Information
Disclaimer
Klasa składowania
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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