236608-M

C-Reactive Protein, Human, Recombinant, E. coli

C-Reactive Protein, Human, Recombinant, E. coli, CAS 9007-41-4, is suitable for immunological studies.

• Synonim(y): C-Reactive Protein, Human, Recombinant, E. coli, rhCRP
• Numer CAS: 9007-41-4
• UNSPSC Code: 12352202
• NACRES: NA.77
• MDL number: MFCD00130690
• Form: liquid
• Recombinant: expressed in E. coli

Właściwości

• recombinant: expressed in E. coli
• Quality Segment: 100
• description: Merck USA index - 14, 2603
• form: liquid
• manufacturer/tradename: Calbiochem^®
• storage condition: do not freeze
• solubility: aqueous buffer: soluble
• storage temp.: 2-8°C

Opis

General description

M.W. 23,000 (monomer); 115,000 (pentamer).

Recombinant, human C-reactive protein expressed in E. coli. CRP is a major acute-phase plasma protein that is dramatically elevated in patients with acute-phase conditions. Composed of five identical noncovalently linked subunits. Exhibits Ca²⁺-dependent binding to a variety of substrates. Important in diagnosis of rheumatoid arthritis. Suitable for immunological studies. In purified states and in plasma the monomeric form (M.W. ~21 kDa) aggregates as a cyclic pentamer. Intended for use as a calibration standard for assays of CRP, for structural and functional studies, and as an antigen for production of antisera.Calibrated by electroimmunoassay against WHO reference standard or equivalent.

Physical form

In 140 mM NaCl, 20 mM Tris-HCl, 2 mM CaCl₂, 0.05% NaN₃, pH 7.5.

Other Notes

Paffen, E., et al. 2004. Arterioscler. Thromb. Vasc. Biol.24, 975.
Ballou, S.P., and Kushner, I. 1992. Adv. Intern. Med. 37, 313.
Stults, N.L., et al. 1987. Anal. Biochem. 161, 567.
Woo, P., et al. 1985. J. Biol. Chem. 260, 13384.
de Beer, F.C., and Pepys, M.B. 1982. J. Immun. Methods 50, 17.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Toxicity: Standard Handling (A)

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable