234101

Coenzyme A trilithium salt

≥94% (UV), solid, cofactor in enzymatic acetyl transfer reactions, Calbiochem^®

• Synonim(y): Coenzyme A, Trilithium Salt
• Wzór empiryczny (zapis Hilla): C₂₁H₃₃N₇O₁₆P₃S · 3Li
• Numer CAS: 18439-24-2
• Masa cząsteczkowa: 785.33
• UNSPSC Code: 12352211
• NACRES: NA.77
• MDL number: MFCD00075848
• Assay: ≥94% (UV)
• Form: solid
• Quality level: 100
• Storage condition: OK to freeze, desiccated (hygroscopic)

Właściwości

• Nazwa produktu: Coenzyme A, Trilithium Salt, Coenzyme A, Trilithium Salt, CAS 18439-24-2, serves as a cofactor in enzymatic acetyl transfer reactions.
• Quality Level: 100
• description: Merck USA index - 14, 2466
• assay: ≥94% (UV)
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, desiccated (hygroscopic)
• color: off-white
• solubility: water: 1 mg/mL
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: [Li+].[Li+].[Li+].[P](=O)([O-])([O-])O[C@@H]1[C@H](O[C@H]([C@@H]1O)[n]2c3ncnc(c3nc2)N)CO[P](=O)([O-])O[P](=O)(OCC([C@@H](O)C(=O)NCCC(=O)NCCS)(C)C)O
• InChI: 1S/C21H36N7O16P3S.3Li/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;;;/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35);;;/q;3*+1/p-3/t11-,14-,15-,16+,20-;;;/m1.../s1
• InChI key: QSCBPHBAFBVXRK-FFKZSOHASA-K

Opis

General description

A cofactor in enzymatic acetyl transfer reactions.

Application

Coenzyme A, Trilithium Salt - CAS 18439-24-2- Calbiochem has been used to study the effects on CoA pathway T-cell anti-tumor immunity in mouse models[1]

Biochem/physiol Actions

Coenzyme A (CoA) is an essential cofactor in living organisms and plays a crucial role in carboxylic acid metabolism, which includes short and long-chain fatty acids. It is a derivative of pantothenic acid. CoA participates in the transport of the acyl group and activates carbonyl groups in the tricarboxylic acid cycle and fatty acid metabolism. Over a hundred different reactions utilize CoA as it is the source of 4′-phosphopantetheine, which acts as a prosthetic group of carrier proteins of polyketide, fatty acid, and non-ribosomal peptide synthases[2]

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable