Przejdź do zawartości
Merck

Kluczowe dokumenty

Wyświetl całą dokumentację

Przejdź do

204885

Dopełniacz C3, ludzki

Complement C3, Human, CAS 80295-41-6, is a native C3 component. Glycoprotein composed of two non-identical disulfide-bonded subunits of 115 kDa (α) and 75 kDa (β).

Synonim(y):

Complement C3, Human

Zaloguj się, aby wyświetlić ceny organizacyjne i kontraktowe.

Wybierz wielkość

Zmień widok
Gabaryty przesyłkiSKUDostępnośćCena netto
250 μg

Dostępne do wysyłki DZISIAJzKuehne + Nagel Sp. z o.o.

1610,00 zł

Informacje o tej pozycji

Numer CAS:
80295-41-6
UNSPSC Code:
12352202
NACRES:
NA.25
MDL number:
MFCD00130836
Form:
liquid
Assay:
≥85% (SDS-PAGE)

1610,00 zł

Dostępne do wysyłki DZISIAJSzczegóły

​
Zamów zamówienie zbiorcze
Pomoc techniczna
Potrzebujesz pomocy? Nasz zespół doświadczonych naukowców chętnie Ci pomoże.
Pozwól nam pomóc

Quality Level

100

assay

≥85% (SDS-PAGE)

form

liquid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

impurities

IgG, IgA, IgM, C4, functionally active C5, albumin or ceruloplasmin, trace

shipped in

wet ice

storage temp.

−70°C

General description

Native, human C3 complement component. Glycoprotein composed of two non-identical disulfide-bonded subunits with M.W. of 115,000 (α) and 75,000 (β). Present in normal human serum at 1.25 mg/ml. Classical and alternative activation pathways of complement converge at the C3 step. Activation via either pathway can result in assembly of C3-cleaving enzymes (C3 convertases) on target surfaces. Both C3 convertases cleave the C3 α-chain at peptide bond 77, resulting in production of C3a (M.W. 9083) and C3b fragments (M.W. 180,000). Released C3a peptide is one of the three complement anaphylatoxins. The nascent C3b fragment can form a covalent ester bond with target surface. The covalent attachment of C3b to target acceptors is required for continuation of complement activation.

Biochem/physiol Actions

>3,000 C₃H₅0 units/mg; ≥60% of the C3 activity in normal human serum on a mg/mg basis.

Physical form

In PBS.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Other Notes

Lambris, J.D. and Muller-Eberhard, H.J. 1986. Mol. Immunol.23, 1237.
Tack, B.F., et al. 1980. Methods Enzymol. 80, 64.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)
Ta strona może zawierać tekst przetłumaczony maszynowo.

Porównaj podobne pozycje

Wyświetl pełne porównanie

Pokaż różnice

1 of 1

Ta pozycja
204876204896204886
Complement C3, Human Complement C3, Human, CAS 80295-41-6, is a native C3 component. Glycoprotein composed of two non-identical disulfide-bonded subunits of 115 kDa (α) and 75 kDa (β).

Sigma-Aldrich

204885

Complement C3, Human

Complement C1q, Human Complement C1q, Human, CAS 80295-33-6, is a native C1q complement component composed of 18 polypeptide chains consisting of three nonidentical A, B, C subunits of 29, 26, and 19 kDa, respectively.

Sigma-Aldrich

204876

Complement C1q, Human

Complement C8, Human Complement C8, Human, CAS 80295-58-5, is a native glycoprotein composed of three non-identical subunits of 64, (α), 64 (β), and 22 kDa (γ).

Sigma-Aldrich

204896

Complement C8, Human

Complement C4, Human Complement C4, Human, CAS 80295-48-3,is a native glycoprotein composed of three non-identical subunits of 93, 75, and 32 kDa linked by disulfide bonds.

Sigma-Aldrich

204886

Complement C4, Human

assay

≥85% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

assay

≥85% (SDS-PAGE)

assay

≥90% (SDS-PAGE)

form

liquid

form

liquid

form

liquid

form

liquid

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

storage temp.

−70°C

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

Klasa składowania

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Ying Wang et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(27), 15818-15826 (2020-06-17)
Atherosclerosis is the process underlying heart attack and stroke. Despite decades of research, its pathogenesis remains unclear. Dogma suggests that atherosclerotic plaques expand primarily via the accumulation of cholesterol and inflammatory cells. However, recent evidence suggests that a substantial portion

Numer pozycji handlu globalnego

SKUNUMER GTIN
204885-250UG04055977219791

Questions

Reviews

No rating value

Active Filters