1.06447

tri-Sodium citrate dihydrate

EMPROVE^® EXPERT, Ph. Eur., BP, ChP, JP, USP, ACS, E 331

• Synonim(y): Sodium citrate tribasic dihydrate, Trisodium Citrate, Sodium Citrate, Dihydrate, Citric acid trisodium salt dihydrate, Trisodium citrate dihydrate
• Wzór liniowy: HOC(COONa)(CH₂COONa)₂ · 2H₂O
• Numer CAS: 6132-04-3
• Masa cząsteczkowa: 294.10
• UNSPSC Code: 12352107
• EC Index Number: 200-675-3
• E Number: E331
• MDL number: MFCD00150031
• Beilstein/REAXYS Number: 6104939

Właściwości

• Quality Level: 500
• agency: USP, BP, ChP, JP, Ph. Eur., suitable for SM 4500 - NH3
• product line: EMPROVE^® EXPERT
• form: solid
• feature: RNase and DNase free
• impurities: endotoxins, low
• pH: 7.5-9.0 (25 °C, 50 g/L in H₂O)
• pKa: (1) 3.1, (2) 4.8, (3) 6.4
• mp: 150 °C (anhydrous substance), >300 °C (lit.)
• application(s): liquid formulation; ophthalmics; parenterals; pharma/biopharma processes; pharmaceutical; semi-solid formulation; solid formulation
• storage temp.: 2-30°C
• SMILES string: O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
• InChI: 1S/C6H8O7.3Na.2H2O/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;;2*1H2/q;3*+1;;/p-3
• InChI key: NLJMYIDDQXHKNR-UHFFFAOYSA-K

Opis

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

tri-Sodium citrate dihydrate is typically used as a citrate buffer system component for biomolecule downstream chromatography steps or final liquid formulation.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable