1.00201

Phenol

EMPROVE^® ESSENTIAL, Ph. Eur., ChP, JP, USP

• Synonim(y): Hydroxybenzene, Carbolic acid, Hydroxybenzene
• Wzór liniowy: C₆H₅OH
• Numer CAS: 108-95-2
• Masa cząsteczkowa: 94.11
• EC Index Number: 203-632-7
• UNSPSC Code: 12352104
• Beilstein/REAXYS Number: 969616
• MDL number: MFCD00002143

Właściwości

• Quality Segment: 500
• agency: ChP, JP, Ph. Eur., USP
• vapor density: 3.24 (vs air)
• vapor pressure: 0.09 psi ( 55 °C), 0.36 mmHg ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• assay: 99.0-100.5% (bromatometric)
• form: solid
• autoignition temp.: 1319 °F
• expl. lim.: 8.6 %
• technique(s): API processing | cocrystal formation: suitable
• pH: 5 (20 °C, 50 g/L in H₂O)
• bp: 182 °C (lit.)
• mp: 40-42 °C (lit.)
• transition temp: flash point 81 °C
• density: 1.071 g/mL at 25 °C (lit.)
• application(s): liquid formulation; pharma/biopharma processes; pharmaceutical
• storage temp.: 15-25°C
• SMILES string: Oc1ccccc1
• InChI: 1S/C6H6O/c7-6-4-2-1-3-5-6/h1-5,7H
• InChI key: ISWSIDIOOBJBQZ-UHFFFAOYSA-N

Opis

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Phenol is active against a wide range of microorganisms and is therefore used as a preservative in pharmaceutical formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H311 + H331,H314,H341,H373,H411
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - STOT RE 2
• target_organs: Nervous system,Kidney,Liver,Skin
• Klasa składowania: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 2
• flash_point_f: 177.8 °F - closed cup
• flash_point_c: 81 °C - closed cup