1.00130

Benzoic acid

powder, EMPROVE^® ESSENTIAL, Ph. Eur., BP, ChP, JP, USP, E 210

• Synonim(y): Benzoic acid, Phenylformic acid, Benzene carboxylic acid
• Wzór empiryczny (zapis Hilla): C₇H₆O₂
• Numer CAS: 65-85-0
• Masa cząsteczkowa: 122.12
• MDL number: MFCD00002398
• UNSPSC Code: 12352106
• E Number: E210
• EC Index Number: 200-618-2

Właściwości

• Quality Level: 500
• agency: BP, ChP, JP, Ph. Eur., USP
• vapor pressure: 0.001 hPa ( 20 °C)
• product line: EMPROVE^® ESSENTIAL
• assay: 99.5-100.5% substance (anhydrous) basis (acidimetric)
• form: powder, solid
• autoignition temp.: 570 °C
• quality: E 210
• technique(s): API processing | cocrystal formation: suitable, API processing | salt formation: suitable
• pH: 2.5-3.5 (20 °C in H₂O, saturated solution)
• bp: 249 °C/1013 hPa
• mp: 121-123 °C
• transition temp: flash point 121 °C
• solubility: water: 2.9 g/L at 25 °C
• density: 1.321 g/cm³ at 20 °C
• anion traces: sulfate (SO₄^2-): ≤0.02%
• cation traces: As: ≤1 ppm, Cd: ≤10 ppm, Cr: ≤2.5 ppm, Cu: ≤10 ppm, Hg: ≤1 ppm, Mn: ≤25 ppm, Ni: ≤2 ppm, Pb: ≤2 ppm, Zn: ≤10 ppm
• application(s): liquid formulation; pharmaceutical; semi-solid formulation
• storage temp.: 15-25°C
• SMILES string: [O-]C(=O)c1ccccc1.[H+]
• InChI: 1S/C7H6O2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H,8,9)
• InChI key: WPYMKLBDIGXBTP-UHFFFAOYSA-N

Opis

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Benzoic acid is typically used as a preservative in pharmaceutical formulations and cosmetics due to its antimicrobial characteristics. It is also used as an additive for the preservation of food.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

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Informacja o środkach bezpieczeństwa

• pictograms: GHS08,GHS05
• signalword: Danger
• hcodes: H315,H318,H372
• pcodes: P260 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P314
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2 - STOT RE 1 Inhalation
• target_organs: Lungs
• Klasa składowania: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable