1.00020

Acetone

for liquid chromatography LiChrosolv^®

• Synonim(y): Dimethyl ketone, Propanone, 2-Propanone
• Wzór liniowy: CH₃COCH₃
• Numer CAS: 67-64-1
• Masa cząsteczkowa: 58.08
• UNSPSC Code: 12191502
• NACRES: NA.03
• EC Index Number: 200-662-2
• MDL number: MFCD00008765
• Beilstein/REAXYS Number: 635680
• Assay: ≥99.8% (GC)
• Grade: HPLC grade
• Technique(s): HPLC: suitable
• Bp: 56 °C/760 mmHg (lit.)
• Vapor pressure: 184 mmHg ( 20 °C)

Właściwości

• grade: HPLC grade
• Quality Segment: 100
• vapor density: 2 (vs air)
• vapor pressure: 184 mmHg ( 20 °C)
• description: isocratic
• product line: LiChrosolv^®
• assay: ≥99.8% (GC)
• form: liquid
• autoignition temp.: 465 °C (DIN 51794)
• potency: 5800 mg/kg LD₅₀, oral (Rat), 20000 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 13.2 %
• technique(s): HPLC: suitable
• impurities: ≤0.0002 meq/g Acidity, ≤0.0002 meq/g Alkalinity, ≤0.05% Water
• evapn. residue: ≤2.0 mg/L
• transmittance: 335 nm, ≥50%, 340 nm, ≥80%, 350 nm, ≥98%
• refractive index: n20/D 1.359 (lit.)
• pH: 5-6 (20 °C, 395 g/L in H₂O)
• capacity: 1000 g/kg water absorbing capacity
• bp: 56 °C/760 mmHg (lit.)
• mp: −94 °C (lit.)
• transition temp: flash point <-20 °C
• density: 0.791 g/mL at 25 °C (lit.)
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC(C)=O
• InChI: 1S/C3H6O/c1-3(2)4/h1-2H3
• InChI key: CSCPPACGZOOCGX-UHFFFAOYSA-N

Opis

General description

LiChrosolv^® solvents show high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level. This makes them ideal for reproducible separations.

Application

Intended for HPLC and UHPLC-MS applications, either as an extraction solvent or as a mobile phase.
Reported for use in LC–MS/MS investigations of:

• blood plasma and serum samples fractionated on several chromatography sorbents
• peptides in animal biological samples

Acetone′s luminesence intensity is dependent upon the solution components . The absorption of UV light by acetone, results in its photolysis and the production of radials .

Features and Benefits

• suitability tested and specified for UHPLC-MS and UHPLC-UV: for analytical flexibility
• specified quality in positive and negative in positive and negative electrospray ionization (ESI) and atmospheric-pressure chemical ionization-mass spectrometry (APCI-MS) for lowest detection limits and confidence in analyses for all important MS modes (test 1)

—ESI/APCI (+) < 2 ppb
—ESI/APCI (-) < 10 ppb

• lowest impurity profile: for interference-free baselines (test 2)
• microfiltered through 0.2 μm filter (test 3) to provide:

—a long lifespan to filters and mechanical parts of HPLC systems
—reduced risk of column clogging

• packed in borosilicate glass bottles for minimized metal ion contaminations
• lowest levels of trace metal impurities for a minimum metal ion adduct formation

—<5 ppb

• lowest level of polyethylene glycol (PEG) impurities in UHPLC-MS solvent lineup (PEG S/N signal-to-noise-ratio < 50)

Preparation Note

Product filtered through a 0.2 μm filter

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• pictograms: GHS02,GHS07
• signalword: Danger
• pcodes: P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• target_organs: Respiratory system
• supp_hazards: EUH066
• Klasa składowania: 3 - Flammable liquids
• wgk: WGK 1
• flash_point_f: 1.4 °F - closed cup
• flash_point_c: -17.0 °C - closed cup
• hcodes: H225,H319,H336