1.00002

Tri-n-butyl phosphate

EMPROVE^® EXPERT, Ph. Eur.

• Synonim(y): Tributyl phosphate, TBP, TBPA
• Wzór liniowy: (CH₃(CH₂)₃O)₃PO
• Numer CAS: 126-73-8
• Masa cząsteczkowa: 266.31
• Beilstein: 1710584
• Numer MDL: MFCD00009436
• Kod UNSPSC: 12352303
• Numer indeksu EC: 204-800-2

Właściwości

• agency: Ph. Eur.
• Poziom jakości: 500
• gęstość pary: 9.2 (vs air)
• ciśnienie pary: 27 mmHg ( 178 °C); 7.3 mmHg ( 150 °C)
• linia produktu: EMPROVE^® EXPERT
• Postać: liquid
• temp. samozapłonu: 770 °F
• współczynnik refrakcji: n20/D 1.424 (lit.)
• tw: 180-183 °C/22 mmHg (lit.)
• mp: −79 °C (lit.)
• temp. przejścia: flash point 146 °C
• rozpuszczalność: 6 g/L
• gęstość: 0.979 g/mL at 25 °C (lit.)
• Zastosowanie: liquid formulation; pharma/biopharma processes; pharmaceutical
• temp. przechowywania: 15-25°C
• ciąg SMILES: CCCCOP(=O)(OCCCC)OCCCC
• InChI: 1S/C12H27O4P/c1-4-7-10-14-17(13,15-11-8-5-2)16-12-9-6-3/h4-12H2,1-3H3
• Klucz InChI: STCOOQWBFONSKY-UHFFFAOYSA-N

Opis

Opis ogólny

Chemicals play an important role in the stabilization of a biologic drug during its manufacturing and formulation process – for instance, by preventing aggregation. We offer a wide range of high-quality stabilizers, buffers and salts to successfully purify and formulate your biomolecules. Specifically developed for high-risk applications, they are low in bioburden and endotoxins.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Zastosowanie

Tri-n-butyl phosphate is used widely as a solvent along with either TritonTM X100 or Tween^® in solvent detergent treatment for viral inactivation procedures especially for plasma derived therapeutics.
Due to its low microbial and endotoxin limits, Tri-n-butyl phosphate Emprove^® Expert is especially suitable for high-risk applications.

Informacje prawne

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

TWEEN is a registered trademark of Croda International PLC

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS08,GHS07
• Hasło ostrzegawcze: Warning
• Zwroty wskazujące rodzaj zagrożenia: H302,H315,H351,H412
• Zwroty wskazujące środki ostrożności: P202 - P264 - P273 - P301 + P312 - P302 + P352 - P308 + P313
• Klasyfikacja zagrożeń: Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Skin Irrit. 2
• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): 293.0 °F - closed cup
• Temperatura zapłonu (°C): 145 °C - closed cup