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A6057
4-Azidophenacyl bromide
powder
Synonim(y):
4′-Azido-2-bromoacetophenone, 4-Azido-α-bromoacetophenone
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Informacje o tej pozycji
Wzór empiryczny (zapis Hilla):
C8H6BrN3O
Numer CAS:
Masa cząsteczkowa:
240.06
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
260-519-5
Beilstein/REAXYS Number:
1961705
MDL number:
form
powder
reaction suitability
reaction type: click chemistry, reagent type: cross-linking reagent
color
yellow
solubility
methanol: 50 mg/mL
storage temp.
2-8°C
SMILES string
BrCC(=O)c1ccc(cc1)N=[N+]=[N-]
InChI
1S/C8H6BrN3O/c9-5-8(13)6-1-3-7(4-2-6)11-12-10/h1-4H,5H2
InChI key
LZJPDRANSVSGOR-UHFFFAOYSA-N
Application
Photoactive, heterobifunctional cross-linking reagent. Typically, the initial reaction couples to sulfhydryl in the pH range 7.0-8.0. Second bonding occurs during UV irradiation (250 nm) via reactive nitrene. The latter bonding is rapid and non-specific.
Disclaimer
Reducing agents such as thiols may reduce the azide to amine and should be avoided. Initial manipulations and coupling should be performed under reduced light.
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Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Flam. Sol. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
Klasa składowania
4.1B - Flammable solid hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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