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L2012

リポポリサッカリド サルモネラ菌 セロタイプ enteritidis由来

purified by gel-filtration chromatography

別名:

LPS

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この商品について

UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:
MFCD00131520
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biological source

Salmonella enterica (Serotype enteritidis)

Quality Level

200

form

lyophilized powder

purified by

gel-filtration chromatography

impurities

<1% Protein

color

white to faint yellow

solubility

water: 4.90-5.10 mg/mL, cloudy to hazy, colorless to faintly yellow

shipped in

ambient

storage temp.

2-8°C

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当該品目
L4774L6011L2262
Lipopolysaccharides from Salmonella enterica serotype enteritidis purified by gel-filtration chromatography

Sigma-Aldrich

L2012

Lipopolysaccharides from Salmonella enterica serotype enteritidis

Lipopolysaccharides from Salmonella enterica serotype enteritidis purified by ion-exchange chromatography

Sigma-Aldrich

L4774

Lipopolysaccharides from Salmonella enterica serotype enteritidis

Lipopolysaccharides from Salmonella enterica serotype enteritidis purified by phenol extraction

Sigma-Aldrich

L6011

Lipopolysaccharides from Salmonella enterica serotype enteritidis

Lipopolysaccharides from Salmonella enterica serotype typhimurium purified by gel-filtration chromatography

Sigma-Aldrich

L2262

Lipopolysaccharides from Salmonella enterica serotype typhimurium

biological source

Salmonella enterica (Serotype enteritidis)

biological source

Salmonella enterica (Serotype enteritidis)

biological source

Salmonella enterica (Serotype enteritidis)

biological source

Salmonella enterica (Serotype typhimurium)

solubility

water: 4.90-5.10 mg/mL, cloudy to hazy, colorless to faintly yellow

solubility

-

solubility

water: 0.90-1.10 mg/mL, slightly hazy to turbid, colorless to faintly yellow

solubility

water: 0.90-1.10 mg/mL, hazy to turbid, colorless to faintly yellow

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

impurities

<1% Protein

impurities

<1% Protein, <1% RNA

impurities

<3% Protein (Lowry)

impurities

<1% Protein

General description

This product is extracted from Salmonella enteritidis and purified by gel filtration. The source strain is ATCC 13076. Lipopolysaccharide from Salmonella enteritidis is mutagenic in murine spleen cells and causes a plaque-forming response in those cells.

Application

リポ多糖類（LPS）はグラム陰性細菌の細胞壁に特徴的な成分です。LPS とその脂質A部分は、Toll 様受容体 4（TLR4）による自然免疫系の細胞を刺激します。

Biochem/physiol Actions

Lipopolysaccharides (LPS) are localized in the outer layer of the membrane and are, in noncapsulated strains, exposed on the cell surface. They contribute to the integrity of the outer membrane, and protect the cell against the action of bile salts and lipophilic antibiotics.

Preparation Note

The product is soluble in water (5 mg/ml) or cell culture medium (1 mg/ml) yielding a hazy, faint yellow solution. A more concentrated, though still hazy, solution (20 mg/ml) has been achieved in aqueous saline after vortexing and warming to 70-80 oC. Lipopolysaccharides are molecules that form micelles in every solvent. Hazy solutions are observed in water and phosphate buffered saline. Organic solvents do not give clearer solutions. Methanol yields a turbid suspension with floaters, while water yields a homogeneously hazy solution.

Other Notes

To gain a comprehensive understanding of our extensive range of Lipopolysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

保管分類

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

L2012-10MG-PW: + L2012-5MG: + L2012-VAR: + L2012-10MG: + L2012-25MG: + L2012-BULK: + L2012-25MG-PW:

jan

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number
0000543953
0000517247
0000517247
0000543953
0000333165

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以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Laman K Mamedova et al.
The Journal of nutritional biochemistry, 24(8), 1499-1507 (2013-03-08)
Saturated free fatty acids (FFA) can activate inflammatory cascades including the toll-like receptor 4 (TLR4) pathway. TLR4 is expressed by hepatocytes and may help link FFA to altered hepatic gluconeogenesis in type 2 diabetes mellitus. This study examined the role
A Zarbock et al.
British journal of pharmacology, 155(3), 357-364 (2008-07-01)
Acute lung injury (ALI) remains a major challenge in critical care medicine. Both neutrophils and chemokines have been proposed as key components in the development of ALI. The main chemokine receptor on neutrophils is CXCR2, which regulates neutrophil recruitment and
Basilia Zingarelli et al.
Immunology, 124(1), 51-57 (2007-11-22)
Peroxisome proliferator activated receptor-gamma (PPARgamma) has been reported to exert anti-inflammatory properties in endotoxic shock and sepsis. One phenomenon that alters the inflammatory response to endotoxin [lipopolysaccharide (LPS)] is endotoxin tolerance, which is caused by previous exposure to endotoxin. Here
Jörg Reutershan et al.
European journal of immunology, 39(6), 1597-1607 (2009-06-06)
The Duffy antigen receptor for chemokines (DARC) has a high affinity for CC and CXC chemokines. However, it lacks the ability to induce cell responses that are typical for classical chemokine receptors. The role of DARC in inflammatory conditions remains
Graciliana Lopes et al.
PloS one, 7(2), e31145-e31145 (2012-02-10)
Bacterial and fungal infections and the emerging multidrug resistance are driving interest in fighting these microorganisms with natural products, which have generally been considered complementary to pharmacological therapies. Phlorotannins are polyphenols restricted to brown seaweeds, recognized for their biological capacity.
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資料

Lipopolysaccharides for Research – Structure, Function & Applications

Explore the structure, function, and diverse applications of Lipopolysaccharides. Discover their role in bacteria, serological specificity, and research potential.

関連コンテンツ

Lipopolysaccharides

Lipopolysaccharide (LPS) is a major component of Gram-negative bacteria, important for microbiological research.

グローバルトレードアイテム番号

カタログ番号GTIN
L2012-10MG04061833272015
L2012-25MG04061833289761

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