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由来生物
rabbit
品質水準
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous glycerol solution
分子量
antigen 100 kDa
化学種の反応性
human, rat
テクニック
dot blot: 1:1000
western blot: 1:1,000 using rat brain extracts
UniProtアクセッション番号
輸送温度
dry ice
保管温度
−20°C
ターゲットの翻訳後修飾
phosphorylation (pSer845)
遺伝子情報
human ... GRIA1(2890)
rat ... Gria1(50592)
詳細
Rabbit Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer845) antibody recognizes human and rat AMPA Receptor, GluR1 subunit (pSer845).
免疫原
synthetic phosphorylated peptide corresponding to a region near serine 845 of rat glutamate receptor subunit GluR1.
アプリケーション
Rabbit Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer845) antibody can be used for western blot analysis at 1:1,000 using rat brain extracts.
ターゲットの説明
AMPA is a transmembrane receptor for glutamate that regulates synapsis in the central nervous system. It is composed of 4 types of subunits, GluR1, 2, 3, 4.
物理的形状
Solution in 10 mM HEPES buffer, pH 7.5, containing 150 mM NaCl, 100 μg/ml BSA and 50% glycerol.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
A4477-VAR:
A4477-100UL:
A4477-150UL-PW:
A4477-150UL:
A4477-BULK:
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Rodrigo Bainy Leal et al.
Molecular psychiatry, 25(3), 655-665 (2018-06-09)
Fear is a conscious state caused by exposure to real or imagined threats that trigger stress responses that affect the body and brain, particularly limbic structures. A sub-group of patients with mesial temporal lobe epilepsy related to hippocampus sclerosis (MTLE-HS)
Kuang-Ti Chen et al.
Frontiers in behavioral neuroscience, 9, 162-162 (2015-07-08)
Sarcosine, an endogenous amino acid, is a competitive inhibitor of the type I glycine transporter and an N-methyl-d-aspartate receptor (NMDAR) coagonist. Recently, we found that sarcosine, an NMDAR enhancer, can improve depression-related behaviors in rodents and humans. This result differs
Loukia Parisiadou et al.
Nature neuroscience, 17(3), 367-376 (2014-01-28)
Leucine-rich repeat kinase 2 (LRRK2) is enriched in the striatal projection neurons (SPNs). We found that LRRK2 negatively regulates protein kinase A (PKA) activity in the SPNs during synaptogenesis and in response to dopamine receptor Drd1 activation. LRRK2 interacted with
M W Lopes et al.
Translational psychiatry, 6(12), e986-e986 (2016-12-14)
Glucocorticoids (GC) released during stress response exert feedforward effects in the whole brain, but particularly in the limbic circuits that modulates cognition, emotion and behavior. GC are the most commonly prescribed anti-inflammatory and immunosuppressant medication worldwide and pharmacological GC treatment
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