A4352

抗AMPAレセプター, GluR1サブユニット, リン酸化型(pSer⁸³¹)抗体 ウサギ宿主抗体

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• 別名: 抗AMPA型グルタミン酸レセプター1, リン酸化型(pSer⁸³¹)抗体
• UNSPSC Code: 12352203
• NACRES: NA.41
• MDL number: MFCD04040522
• Conjugate: unconjugated
• Clone: polyclonal
• Application: ELISA (d), IHC, IP, WB
• Citations: 7

特性

• biological source: rabbit
• Quality Segment: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 100 kDa
• species reactivity: rat, human
• concentration: ~1 mg/mL
• technique(s): direct ELISA: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: 1:1,000 using rat brain (hippocampal) homogenate
• UniProt accession no.: P42261
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer831)
• Gene Information: human ... GRIA1(2890) ; rat ... Gria1(50592)

詳細

General description

AMPA is a transmembrane receptor for glutamate that regulates synapsis in the central nervous system. It is composed of 4 types of subunits, GluR1, 2, 3, 4.

GluR1 subunits of AMPA receptors are membrane proteins that regulate synaptic plasticity of the central nervous system. This receptor has also been implicated in spatial memory retention. Phosphorylation of serine 831 in GluR1 subunit of the AMPA receptor modulates long-term potentiation in neuronal synapses. Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸³¹) antibody is specific for the GluR1 subunit (phosphorylated on serine 831) of the AMPA receptor in rats and humans.

Immunogen

ラットグルタミン酸レセプタ-サブユニットGluR1のセリン831近傍領域に相当する合成リン酸化ペプチド。

The GluR1 sequence is conserved among species and has partial homology to VGLUT2.

Application

Anti-phospho-AMPA Receptor, GluR1 Subunit (pSer⁸³¹) antibody is suitable for use in direct ELISA, immunohistochemistry, immunoblot and immunoprecipitation. The antibody may also be used for western blot (1:1,000 using rat hippocampal homogenate).

Physical form

10mM HEPESバッファ-溶液 (pH 7.5, 150mM NaCl, 100μg/mL BSA, 50%グリセロ-ル含有)。

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類: 10 - Combustible liquids
• 一体何が起きているの？: WGK 1
• 引火点 (F): Not applicable
• 引火点（°C）: Not applicable