A231

アラキドニルトリフルオロメチルケトン

oil, ≥97% (NMR)

• 別名: 1,1,1-トリフルオロメチル-6,9,12,15-ヘニコサテトラエン-2-オン, AACOCF₃, Arach-CF₃
• 実験式（ヒル表記法）: C₂₁H₃₁F₃O
• CAS番号: 149301-79-1
• 分子量: 356.47
• NACRES: NA.77
• PubChem Substance ID: 24890647
• UNSPSC Code: 51111800
• MDL number: MFCD00236427

特性

• Quality Segment: 100
• assay: ≥97% (NMR)
• form: oil
• storage condition: desiccated, protect from light, under inert gas
• color: yellow
• solubility: DMSO: >5 mg/mL
• storage temp.: −20°C
• SMILES string: CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)C(F)(F)F
• InChI: 1S/C21H31F3O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(25)21(22,23)24/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-19H2,1H3/b7-6-,10-9-,13-12-,16-15-
• InChI key: PLWROONZUDKYKG-DOFZRALJSA-N
• Gene Information: human ... PLA2G1B(5319)

詳細

Application

Arachidonyl trifluoromethyl ketone (AACOCF3) has been used as a anandamide degradation inhibitor to study its effects in primary astrocyte cultures.

Biochem/physiol Actions

Arachidonyl trifluoromethyl ketone (AACOCF3) plays a role in the inhibition of 12-hydroxyeicosatetraenoic acid (12-HETE) and thromboxane B2 produced by the platelets.

in vitroでアナンダミドの加水分解を阻害します。ホスホリパ-ゼA₂を阻害します。

Features and Benefits

This compound is featured on the Phospholipase A2 page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

吸湿性であり、光および空気中で不安定です。

安全性情報

• 保管分類: 10 - Combustible liquids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)