I9783
Monoclonal Anti-Importin α3 antibody produced in rat
clone 3D10, purified immunoglobulin, buffered aqueous solution
別名:
Anti-Imp α
ログインで組織・契約価格をご覧ください。
この商品について
Conjugate:
unconjugated
Clone:
3D10, monoclonal
Application:
ARR, WB
Citations:
4
biological source
rat
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
3D10, monoclonal
form
buffered aqueous solution
mol wt
antigen ~60 kDa
species reactivity
mouse, hamster, bovine, canine, rat, human, monkey
technique(s)
microarray: suitable, western blot: 2-4 μg/mL using HeLa cell extract
isotype
IgG2a
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... KPNA4(3840)
mouse ... Kpna4(16649)
rat ... Kpna4(361959)
Immunogen
recombinant mouse importin α3/Qip1.
Biochem/physiol Actions
The gene KPNA4 (karyopherin subunit α 4) encodes a 16kDa protein, also referred to as importin α 3 belonging to the family of karyopherins (designated KPNA1 to KPNA4), that participates in the recognition of NLS (nuclear localization signal) sites and dock NLS-containing proteins destined for transport into the nuclear pore complex. It binds to translocon and participates in the sorting of INM (inner nuclear membrane)-directed integral membrane proteins. It associates with nucleoporins and functions in cargo-translocation across the nuclear membrane.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, and 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Still not finding the right product?
製品選択ツール}で選択肢を絞り込んでください。
保管分類
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
関連コンテンツ
Datasheet
KPNA4 Mediates Vitamin D-Dependent Inhibition of NF-kB Activity in Swine Epicardial Preadipocytes.
Chen S
Circulation, A12818-A12818 (2014)
Annett Koch et al.
Cell cycle (Georgetown, Tex.), 10(8), 1200-1207 (2011-03-18)
It is well established that mutual relations exist between the oxidative status of a cell and the ubiquitin proteasome system (UPS). Oxidation of proteins leads to misfolding and thus claims a higher proteolytic activity of the UPS to dispose these
Sharon C Braunagel et al.
Proceedings of the National Academy of Sciences of the United States of America, 104(22), 9307-9312 (2007-05-23)
Spodoptera frugiperda (Sf9) importin-alpha-16 is a translocon-associated protein that participates in the early sorting pathway of baculovirus integral membrane proteins destined for the inner nuclear membrane (INM). To discern whether sorting intermediate protein complexes like those observed in insect cells