F7016

フルメキン

≥97.0% (HPLC)

• 別名: 9-Fluoro-5-methyl-1-oxo-1,5,6,7-tetrahydropyrido[3,2,1-ij]quinoline-2-carboxylic acid
• 実験式（ヒル表記法）: C₁₄H₁₂FNO₃
• CAS番号: 42835-25-6
• 分子量: 261.25
• UNSPSC Code: 51102829
• NACRES: NA.85
• PubChem Substance ID: 24894926
• EC Number: 255-962-6
• Beilstein/REAXYS Number: 490724
• MDL number: MFCD00079298

特性

• assay: ≥97.0% (HPLC)
• form: powder
• color: white to off-white
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: DNA synthesis | interferes, enzyme | inhibits
• SMILES string: CC1CCc2cc(F)cc3C(=O)C(=CN1c23)C(O)=O
• InChI: 1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)
• InChI key: DPSPPJIUMHPXMA-UHFFFAOYSA-N

詳細

General description

Chemical structure: fluoroquinolone

Biochem/physiol Actions

Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited .

安全性情報

• 保管分類: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)