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B0806

抗BACE 1, C末端(485-501)抗体ウサギ宿主抗体

Name: 抗BACE 1, C末端(485-501)抗体 ウサギ宿主抗体
Brand: SIGMA

affinity isolated antibody, buffered aqueous solution

別名:

抗β-部位APP切断酵素抗体

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この商品について

UNSPSC Code:

12352203

NACRES:

NA.43

MDL number:

MFCD03454775

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ARR, WB

Citations:

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特性

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 70 kDa

species reactivity

human

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

technique(s)

microarray: suitable, western blot: 1:1,000 using a whole cell extract from the human kidney HEK293 cell line stably transfected with human BACE-1

UniProt accession no.

P56817

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... BACE1(23621)

詳細

General description

BACE-1 (β-site APP cleaving enzyme, Asp2 or memapsin 2) is known as β-secretase. BACE-1 is highly expressed in neurons, the major site of Aβ generation. BACE-1 is localized within the Golgi and endosomal compartments, among the several intracellular sites where Aβ is thought to be produced. It constitutes the predominant β-secretase activity in human brain tissue.

Immunogen

ヒトBACE-1のC末端(アミノ酸 485-501)に相当する合成ペプチド。

Application

Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit has been used in western blotting.

Biochem/physiol Actions

Overexpression of β-site APP cleaving enzyme (BACE-1) leads to increased β-secretase activity while displaying appropriate cleavage site specificity for amyloid precursor protein (APP).

Physical form

0.01M PBS溶液 (pH 7.4, 1%BSA, 15mMアジ化ナトリウム含有)。

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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当該品目	B0681	SAB2100200	A3356
Sigma-Aldrich B0806 Anti-BACE 1, C-Terminus (485-501) antibody produced in rabbit	Sigma-Aldrich B0681 Anti-BACE 1, N-Terminus (46-62) antibody produced in rabbit	Sigma-Aldrich SAB2100200 Anti-BACE1 antibody produced in rabbit	Sigma-Aldrich A3356 Anti-β-Amyloid (22-35) antibody produced in rabbit
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Quality Level 200	Quality Level 200	Quality Level 100	Quality Level 200
technique(s) microarray: suitable, western blot: 1:1,000 using a whole cell extract from the human kidney HEK293 cell line stably transfected with human BACE-1	technique(s) western blot: 1:1,000 using a whole cell extract from the human kidney HEK293 cell line stably transfected with human BACE-1	technique(s) immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable	technique(s) indirect ELISA: 0.2-0.4 μg/mL using β-amyloid peptide (22-35), western blot: 0.25-0.5 μg/mL using β-amyloid peptide (1-40)
mol wt antigen 70 kDa	mol wt antigen 60-75 kDa	mol wt 51 kDa	mol wt antigen ~4 kDa

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保管分類

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

B0806-BULK: + IXO11217: + B0806-VAR: + B0806-.2ML:

jan

最新バージョンのいずれかを選択してください：

試験成績書（COA）

Lot/Batch Number

087M4882V

101K4871

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グローバルトレードアイテム番号

カタログ番号	GTIN
B0806-.2ML	04061838102416

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