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Quality Segment
product line
Novabiochem®
form
beads
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
amine
storage temp.
2-30°C
General description
This support comprises the modified Rink amide linker attached via norleucine to aminomethylpolystyrene, and is an ideal tool for the Fmoc SPPS of peptide amides. Cleavage from this resin can be effected by a single step treatment with 95% TFA, providing peptide amides in high yields and purities.
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins
Application
- Second generation amphiphilic poly-lysine dendrons inhibit glioblastoma cell proliferation without toxicity for neurons or astrocytes: Uses Rink Amide AM resin with a 0.71mmol/g loading capacity for synthesizing amphiphilic dendritic amides. (Janiszewska et al., 2016).
- The Role of Phosphoglycans in the Susceptibility of Leishmania mexicana to the Temporin Family of Anti-Microbial Peptides: Describes peptide synthesis on Rink Amide AM resin with a 0.79 mmol/g loading capacity. (Eggimann et al., 2015).
Analysis Note
Colour (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH2Cl2): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.1 ml/g
Identity (of the substitution): passes test
The polymer matrix is copoly (styrene-1 % DVB), 200 -400 mesh.
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH2Cl2): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.1 ml/g
Identity (of the substitution): passes test
The polymer matrix is copoly (styrene-1 % DVB), 200 -400 mesh.
Other Notes
Replaces: 01-64-0038
Legal Information
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany
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当該品目 | |||
|---|---|---|---|
| reaction suitability reaction type: Fmoc solid-phase peptide synthesis | reaction suitability reaction type: Fmoc solid-phase peptide synthesis | reaction suitability reaction type: Fmoc solid-phase peptide synthesis | reaction suitability reaction type: Fmoc solid-phase peptide synthesis |
| functional group amine | functional group amine | functional group amine | functional group amine |
| product line Novabiochem® | product line Novabiochem® | product line Novabiochem® | product line Novabiochem® |
| Quality Level 400 | Quality Level 400 | Quality Level 400 | Quality Level 200 |
| application(s) peptide synthesis | application(s) peptide synthesis | application(s) peptide synthesis | application(s) peptide synthesis |
| form beads | form powder | form beads | form beads |
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。



