C4018
Choloylglycine Hydrolase from Clostridium perfringens (C. welchii)
lyophilized powder, ≥100 units/mg protein
Sinonimo/i:
3α,7α,12α-Trihydroxy-5β-cholan-24-oylglycine amidohydrolase
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Cambia visualizzazione
| Taglio della confezione | SKU | Disponibilità | Prezzo |
|---|---|---|---|
| 1500 units | Per informazioni sulla disponibilità, contatta il Servizio Clienti. | 265,00 € | |
| 3000 units | Per informazioni sulla disponibilità, contatta il Servizio Clienti. | 502,00 € | |
| 7500 units | Per informazioni sulla disponibilità, contatta il Servizio Clienti. | 1.000,00 € 850,00 € |
Informazioni su questo articolo
Numero CAS:
UNSPSC Code:
12352204
NACRES:
NA.54
MDL number:
Specific activity:
≥100 units/mg protein
265,00 €
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Servizio Tecnico
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Permettici di aiutartiform
lyophilized powder
Quality Level
specific activity
≥100 units/mg protein
composition
Protein, ≥50% biuret
shipped in
wet ice
storage temp.
−20°C
Application
Biochem/physiol Actions
The enzyme is an N-terminal nucleophilic (Ntn) hydrolase that catalyzes the hydrolysis of amide bonds, liberates the glycine/taurine moiety from the steroid core and eventually yields unconjugated bile acids. Agents that oxidize thiol groups (e.g., p-mercuribenzoate, iodoacetamide, Hg2+, Cu2+, and Cd2+) have been shown to strongly inhibit bile salt hydrolase (BSH) activity in Clostridium perfringens.[3]
Physical form
Partially purified lyophilized powder containing buffer salts and stabilizer
Other Notes
One unit will hydrolyze 1.0 μmole of glycocholic acid to glycine and cholic acid in 5 min at pH 5.6 at 37 °C.
1 of 1
Questo articolo | |||
|---|---|---|---|
| specific activity ≥100 units/mg protein | specific activity - | specific activity - | specific activity - |
| form lyophilized powder | form powder | form powder | form powder |
| storage temp. −20°C | storage temp. room temp | storage temp. −20°C | storage temp. −20°C |
| shipped in wet ice | shipped in ambient | shipped in dry ice | shipped in dry ice |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level - |
| composition Protein, ≥50% biuret | composition - | composition - | composition - |
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Maksim Rossocha et al.
Biochemistry, 44(15), 5739-5748 (2005-04-13)
Bacterial bile salt hydrolases catalyze the degradation of conjugated bile acids in the mammalian gut. The crystal structures of conjugated bile acid hydrolase (CBAH) from Clostridium perfringens as apoenzyme and in complex with taurodeoxycholate that was hydrolyzed to the reaction
M Victoria Delpino et al.
Archives of microbiology, 191(7), 571-581 (2009-05-14)
The virB genes coding type IV secretion system are necessary for the intracellular survival and replication of Brucella spp. In this study, extracellular proteins from B. abortus 2308 (wild type, WT) and its isogenic virB10 polar mutant were compared. Culture
J M Lambert et al.
Journal of agricultural and food chemistry, 56(18), 8360-8364 (2008-08-30)
The interest in efficient intestinal delivery of health-promoting substances is increasing. However, the delivery of vulnerable substances such as enzymes requires specific attention. The transit through the stomach, where the pH is very low, can be detrimental to the enzymatic
Numero articolo commerciale globale
| SKU | GTIN |
|---|---|
| C4018-1.5KU | 04061832755304 |
| C4018-7.5KU | 04061832755328 |
| C4018-3KU | 04061832755311 |