The water content can be found on the lot-dependent Certificate of Analysis.
P0037
PP242 hydrate
≥98% (HPLC), powder
Sinonimo/i:
2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol
Autenticati per visualizzare i prezzi organizzativi e contrattuali.
Scegli un formato
Cambia visualizzazione
| Taglio della confezione | SKU | Disponibilità | Prezzo |
|---|---|---|---|
| 5 mg | Per informazioni sulla disponibilità, contatta il Servizio Clienti. | 266,00 € |
Informazioni su questo articolo
Formula empirica (notazione di Hill):
C16H16N6O · xH2O
Numero CAS:
Peso molecolare:
308.34 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
266,00 €
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
Servizio Tecnico
Hai bisogno di aiuto? Il nostro team di scienziati qualificati è a tua disposizione.
Permettici di aiutartiQuality Segment
assay
≥98% (HPLC)
form
powder
color
off-white
solubility
DMSO: >10 mg/mL
storage temp.
2-8°C
SMILES string
O.CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c4c(N)ncnc14
InChI
1S/C16H16N6O.H2O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12;/h3-8,20,23H,1-2H3,(H2,17,18,19);1H2
InChI key
FMDOLJSFPXFBIL-UHFFFAOYSA-N
Application
PP242 hydrate has been used:
- as a mammalian target of rapamycin (mTOR) inhibitor to study its effects on rat fibroblast mTOR complex 1 and 2 (mTORC1 & 2) signaling
- as an mTOR inhibitor to treat mouse embryonic fibroblasts (MEF) and cumulus cells (CCs) to study its effects on reactivation of embryonic nucleoli and ribosome biogenesis
- as a target of rapamycin (TOR) kinase inhibitor for the treatment of Arabidopsis to study its effects against Fusarium graminearum infection
Biochem/physiol Actions
PP242 is a potent and selective mTOR inhibitor.
PP242 is a potent and selective mTOR inhibitor. PP242 is a first selective inhibitor that targets ATP domain of mTOR.
Features and Benefits
This compound is featured on the PKB/Akt page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
1 of 1
Questo articolo | |||
|---|---|---|---|
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. −20°C |
| solubility DMSO: >10 mg/mL | solubility DMSO: >10 mg/mL | solubility DMSO: >10 mg/mL | solubility H2O: 10 mg/mL, clear, DMSO: 5 mg/mL, clear (warmed) |
| color off-white | color white to off-white | color off-white | color white to beige |
Classe di stoccaggio
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Scegli una delle versioni più recenti:
Possiedi già questo prodotto?
I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.
Articoli
We offer many products related to PKB/Akt for your research needs.
Numero articolo commerciale globale
| SKU | GTIN |
|---|---|
| P0037-25MG | 04061832434100 |
| P0037-5MG | 04061834261964 |
-
I would like to get information about the water content of the compound. It is written as X in the compound formula. How many water molecules are found in the PP242 hydrate molecule?
1 risposta-
Utile?
-
-
What is the degree of hydration for this product?
1 risposta-
The specification for the degree of hydration for this product is an elemental analysis value of H2O (moles) ranging from 0.0 to 3.0. The actual value can be found in the batch-specific Certificate of Analysis.
Utile?
-