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B019

Phenoxybenzamine hydrochloride

≥97%, powder

Sinonimo/i:

N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride

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Taglio della confezioneSKUDisponibilitàPrezzo
250 mg
Per informazioni sulla disponibilità, contatta il Servizio Clienti.
121,00 €

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C18H22ClNO · HCl
Numero CAS:
Peso molecolare:
340.29
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
200-569-7
MDL number:
Assay:
≥97%
Form:
powder
Quality level:

121,00 €


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Quality Level

assay

≥97%

form

powder

color

white

solubility

H2O: slightly soluble, alcohol: soluble, propylene glycol: soluble

originator

Wellspring

storage temp.

2-8°C

SMILES string

Cl[H].CC(COc1ccccc1)N(CCCl)Cc2ccccc2

InChI

1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H

InChI key

VBCPVIWPDJVHAN-UHFFFAOYSA-N

Biochem/physiol Actions

Calmodulin antagonist; α-adrenoceptor antagonist.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Wellspring. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Questo articolo
SML0667C8417SML0036
form

powder

form

powder

form

solid

form

powder

assay

≥97%

assay

≥98% (HPLC)

assay

≥98%

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

2-8°C

solubility

H2O: slightly soluble, propylene glycol: soluble, alcohol: soluble

solubility

H2O: 15 mg/mL, clear

solubility

H2O: 48 mg/mL, 0.1 M NaOH: 7 mg/mL, ethanol: soluble

solubility

DMSO: ≥18 mg/mL

color

white

color

white to beige

color

white

color

white to tan


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pictograms

Health hazardExclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges



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Certificati d'analisi (COA)

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Articoli

Discover Bioactive Small Molecules for ADME/Tox


David J Unett et al.
The Journal of pharmacology and experimental therapeutics, 347(3), 645-659 (2013-09-21)
The kinetics of drug-receptor interactions can profoundly influence in vivo and in vitro pharmacology. In vitro, the potencies of slowly associating agonists may be underestimated in assays capturing transient signaling events. When divergent receptor-mediated signaling pathways are evaluated using combinations
Y M Ning et al.
Molecular endocrinology (Baltimore, Md.), 10(1), 14-23 (1996-01-01)
The glucocorticoid receptor (GR) is a ligand-regulated transcription factor whose ability to bind hormone is thought to be dependent on association with the 90-kDa heat shock protein (hsp90). In the present study, we have generated a novel form of the
Chandra Srinivasan et al.
Congenital heart disease, 4(5), 329-337 (2009-09-11)
In the past decade, many advances in the care of patients undergoing the Norwood procedure (NP) have been reported, but management remains nonstandardized at many institutions. We studied the impact of a standardized management protocol for neonates undergoing NP. Care



Numero articolo commerciale globale

SKUGTIN
B019-250MG04061833419571

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