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07-601

Anti-TTF-1 Antibody

Name: Anti-TTF-1 Antibody
Brand: MM

serum, Upstate^®

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Informazioni su questo articolo

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, IP, WB

Citations:

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Proprietà

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, human

manufacturer/tradename

Upstate^®

technique(s)

immunohistochemistry: suitable, immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

NM_003317.3

UniProt accession no.

P43699

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... A1CF(29974)

Descrizione

General description

42kDa

Immunogen

6His fusion protein corresponding to full-length TTF-1 (Thyroid transcription factor 1, also known as Thyroid nuclear factor 1, Homeobox protein Nkx-2.1)

Application

Anti-TTF-1 Antibody is a high quality Rabbit Polyclonal Antibody for the detection of TTF-1 & has been validated in IP, WB & IHC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

Biochem/physiol Actions

TTF-1

Physical form

Serum

rabbit antiserum containing 0.05% sodium azide before the addition of glycerol to 30%

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on nuclear extract from H441 human lung epithelial cells

Other Notes

Replaces: MABE513

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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1 of 1

Questo articolo	SAB5500187	SAB1404472	SAB1409740
Sigma-Aldrich 07-601 Anti-TTF-1 Antibody	Sigma-Aldrich SAB5500187 Anti-Thyroid Transcription Factor-1 antibody, Rabbit monoclonal	Sigma-Aldrich SAB1404472 Monoclonal Anti-TITF1 antibody produced in mouse	Sigma-Aldrich SAB1409740 Monoclonal Anti-NKX2-1 antibody produced in mouse
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
clone polyclonal	clone SP141, monoclonal	clone 2F6, monoclonal	clone 1G2, monoclonal
antibody form serum	antibody form affinity isolated antibody	antibody form purified immunoglobulin	antibody form purified immunoglobulin
biological source rabbit	biological source rabbit	biological source mouse	biological source mouse
species reactivity mouse, rat, human	species reactivity human (tested)	species reactivity human	species reactivity human
shipped in wet ice	shipped in wet ice	shipped in dry ice	shipped in dry ice

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Classe di stoccaggio

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Determination of lung as the primary site of cerebral metastatic adenocarcinomas using monoclonal antibody to thyroid transcription factor-1.

R J Bohinski et al.

Journal of neuro-oncology, 40(3), 227-231 (1999-03-05)

Determining the primary site of a cerebral metastatic adenocarcinoma is complicated by the histologic similarity of most adenocarcinomas. Thyroid Transcription Factor-1 (TTF-1) is a highly specific marker of peripheral airway cell neoplasms. Formalin fixed tissue from 30 patients with brain

Utility of surfactant protein B precursor and thyroid transcription factor 1 in differentiating adenocarcinoma of the lung from malignant mesothelioma.

A Khoor et al.

Human pathology, 30(6), 695-700 (1999-06-22)

Differentiation of malignant mesothelioma from adenocarcinoma, particularly from a lung primary, remains a difficult diagnostic problem. Surfactant protein B precursor (pro-SP-B) and thyroid transcription factor 1 (ITF-1) are expressed selectively in the normal respiratory epithelium and in adenocarcinomas of the

ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer.

Karine Pozo et al.

iScience, 24(9), 102953-102953 (2021-09-02)

Lineage-defining transcription factors (LTFs) play key roles in small-cell lung cancer (SCLC) pathophysiology. Delineating the LTF-regulated genes operative in SCLC could provide a road map to identify SCLC dependencies. We integrated chromatin landscape and transcriptome analyses of patient-derived SCLC preclinical

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Numero articolo commerciale globale

SKU	GTIN
07-601	04053252588563

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