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1012780

USP

Alendronate sodium

Name: Alendronate sodium
Brand: USP
Price: 405 EUR

United States Pharmacopeia (USP) Reference Standard

Sinonimo/i:

Alendronate sodium trihydrate, 4-amino-1-hydroxy-1-phosphonobutyl phosphonic acid, monosodium, MK-217

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Taglio della confezione	SKU	Disponibilità	Prezzo
200 mg		Per informazioni sulla disponibilità, contatta il Servizio Clienti.	405,00 €

Informazioni su questo articolo

Formula empirica (notazione di Hill):

C₄H₁₂NaNO₇P₂ · 3 H₂O

Numero CAS:

121268-17-5

Peso molecolare:

325.12

NACRES:

NA.24

PubChem Substance ID:

329748953

UNSPSC Code:

41116107

MDL number:

MFCD01748233

405,00 €

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Proprietà

grade

pharmaceutical primary standard

API family

alendronate

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[Na+].[H]O[H].[H]O[H].[H]O[H].NCCCC(O)(P(O)(O)=O)P(O)([O-])=O

InChI

1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2/q;+1;;;/p-1

InChI key

DCSBSVSZJRSITC-UHFFFAOYSA-M

Gene Information

human ... FDPS(2224)

Descrizione

General description

Alendronate sodium is a primary amino bisphosphonate.[1]

Application

Alendronate sodium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

Alendronate sodium trihydrate is a bone resorption inhibitor; farnesyl diphosphate synthase inhibitor (IC₅₀= 460 nM); CD45 protein tyrosine phosphatase inhibitor.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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Questo articolo	Y0001727	BP830	PHR1599
USP 1012780 Alendronate sodium	Y0001727 Sodium alendronate trihydrate	BP830 Sodium alendronate	Supelco PHR1599 Alendronate Sodium
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename BP	manufacturer/tradename -
format neat	format neat	format neat	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
Gene Information human ... FDPS(2224)	Gene Information human ... FDPS(2224)	Gene Information human ... FDPS(2224)	Gene Information human ... FDPS(2224)
API family alendronate	API family alendronate	API family alendronate	API family alendronate

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P301 + P312 + P330

Hazard Classifications

Acute Tox. 4 Oral

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Ghrelin against alendronate-induced gastric damage in rats.

S O Işeri et al.

The Journal of endocrinology, 187(3), 399-406 (2006-01-21)

Alendronate sodium, a primary amino bisphosphonate, is widely used in the treatment of various diseases that are associated with bone resorption, such as postmenopausal osteoporosis and Paget's disease of bone. Although the adverse effects of biphosphonates on the gastrointestinal system

Alendronate sodium hydrate (oral jelly) for the treatment of osteoporosis: review of a novel, easy to swallow formulation.

Kazuhiro Imai

Clinical interventions in aging, 8, 681-688 (2013-06-15)

Osteoporosis is a skeletal disorder characterized by loss of bone mass, decreased bone strength, and an increased risk of bone fracture. The disease progresses with age, especially in postmenopausal women. Japan is one of the most rapidly aging societies worldwide.

Adaptive growth factor delivery from a polyelectrolyte coating promotes synergistic bone tissue repair and reconstruction.

Nisarg J Shah et al.

Proceedings of the National Academy of Sciences of the United States of America, 111(35), 12847-12852 (2014-08-20)

Traumatic wounds and congenital defects that require large-scale bone tissue repair have few successful clinical therapies, particularly for craniomaxillofacial defects. Although bioactive materials have demonstrated alternative approaches to tissue repair, an optimized materials system for reproducible, safe, and targeted repair

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Numero articolo commerciale globale

SKU	GTIN
1012780-200MG	04061838667496

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