M5284
IgG1 Isotype Control from murine myeloma
clone MOPC 21, purified immunoglobulin, buffered aqueous solution
Sinonimo/i:
Isotype control antibody
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About This Item
Codice UNSPSC:
12352203
NACRES:
NA.46
Prodotti consigliati
Origine biologica
mouse
Coniugato
unconjugated
Forma dell’anticorpo
purified immunoglobulin
Clone
MOPC 21, monoclonal
Forma fisica
buffered aqueous solution
tecniche
flow cytometry: suitable
Condizioni di spedizione
wet ice
Temperatura di conservazione
2-8°C
modifica post-traduzionali bersaglio
unmodified
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Descrizione generale
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. An immunoglobulin has two heavy chains and two light chains connected by a disulfide bond. It is a glycoprotein. IgG is a major class of immunoglobulin. Mouse consists of five immunoglobulin classes- IgM, IgG, IgA, IgD and IgE. Mouse IgG is further divided into five classes- IgG1, IgG2a, IgG2b and IgG3.
Specificità
IgG1 isotype control antibody is specific for anti-mouse whole serum and anti-mouse IgG1. The product does not react with antisera to mouse IgA, IgM, IgG2a, IgG2b, and IgG3.
Applicazioni
IgG1 Isotype Control from murine myeloma has been used in:
extracellular DNA fluorescence assay
extracellular DNA fluorescence assay
- reactive oxygen species (ROS) production analysis
- immunohistochemistry
- double labelling immunohistochemistry
- immunofluorescence
- flow cytometry
- immunoprecipitation
IgG1 isotype control antibodies are suitable for use in immunohistochemistry (7μg/ml) and immunoblotting. The product may also be used for flow cytometry.
Azioni biochim/fisiol
Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice . I
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III reactions. It mainly helps in immune defense. IgG helps in opsonization, complement fixation and antibody dependent cell mediated cytotoxicity.
Stato fisico
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide
Esclusione di responsabilità
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
Certificati d'analisi (COA)
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