M104

(±)-Muscarine chloride hydrate

≥98% (HPLC)

• Sinonimo/i: Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate
• Formula empirica (notazione di Hill): C₉H₂₀ClNO₂ · xH₂O
• Numero CAS: 2936-25-6
• Peso molecolare: 209.71 (anhydrous basis)
• NACRES: NA.77
• PubChem Substance ID: 24278578
• UNSPSC Code: 12352200
• MDL number: MFCD00055067
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Proprietà

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white
• solubility: deionized water: ≥20 mg/mL
• storage temp.: room temp
• SMILES string: [Cl-].CC1OC(CC1O)C[N+](C)(C)C
• InChI: 1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1
• InChI key: WUFRNEJYZWHXLC-UHFFFAOYSA-M
• Gene Information: human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Descrizione

Application

(±)-Muscarine chloride hydrate may be used:

• as an acetylcholine receptor agonist in neuronal precursor cell lines PC 12 cells
• as toxin test compound for paper spray mass spectrometry (PSMS) optimization experiments[1]
• as a component of quality control(QC) in hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry (HILIC-HRMS/MS) analysis of human urine samples[2]

Biochem/physiol Actions

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases.[3] Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.[3]

Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H319
• pcodes: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves