C2901

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated

≥95% (HPLC), powder

• Sinonimo/i: CCK-8, non-sulfated
• Formula empirica (notazione di Hill): C₄₉H₆₂N₁₀O₁₃S₂
• Numero CAS: 25679-24-7
• Peso molecolare: 1063.21
• NACRES: NA.32
• PubChem Substance ID: 24892546
• UNSPSC Code: 12352202
• MDL number: MFCD00076488
• Assay: ≥95% (HPLC)
• Form: powder

Proprietà

• Quality Segment: 200
• assay: ≥95% (HPLC)
• form: powder
• UniProt accession no.: P06307
• storage temp.: −20°C
• SMILES string: CSCCC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(N)CC(O)=O)C(=O)NCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(CCSC)C(=O)NC(CC(O)=O)C(=O)NC(Cc4ccccc4)C(N)=O
• InChI: 1S/C49H62N10O13S2/c1-73-18-16-34(55-47(70)37(21-28-12-14-30(60)15-13-28)58-44(67)32(50)23-41(62)63)45(68)53-26-40(61)54-38(22-29-25-52-33-11-7-6-10-31(29)33)48(71)56-35(17-19-74-2)46(69)59-39(24-42(64)65)49(72)57-36(43(51)66)20-27-8-4-3-5-9-27/h3-15,25,32,34-39,52,60H,16-24,26,50H2,1-2H3,(H2,51,66)(H,53,68)(H,54,61)(H,55,70)(H,56,71)(H,57,72)(H,58,67)(H,59,69)(H,62,63)(H,64,65)
• InChI key: OIXQINQYMGNCII-UHFFFAOYSA-N
• Gene Information: human ... CCK(885)

Descrizione

Application

Cholecystokinin (CCK) Fragment 26-33 Amide, Non-sulfated has been used in the specificity testing against gastrin and pepsinogen I proteins.

Biochem/physiol Actions

Biologically inactive form of CCK-8; CCK_B/gastrin receptor agonist that has no activity at the CCK_A receptor.

Cholecystokinin (CCK) is a 115 amino acid preprohormone and a neurotransmitter. It exists in many isoforms. The octapeptide of CCK (CCK-8S) is the most abundant form. CCK is mapped to human chromosome 3p22.1. CCK interacts with receptors of the gastrointestinal tract and nervous system. Polymorphisms in the CCK is implicated in hallucinations in patients with Parkinson′s disease. CCK plays a key role in the activation of the calcineurin-regulated nuclear factor of activated T-cells (NFATs).

Informazioni sulla sicurezza

• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)