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B5057

Sigma-Aldrich

7-Benzyloxy-4-trifluoromethylcoumarin

≥99% (HPLC), solid

Sinonimo/i:

7-BFC

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About This Item

Formula empirica (notazione di Hill):
C17H11F3O3
Peso molecolare:
320.26
Numero MDL:
Codice UNSPSC:
12161501
ID PubChem:
NACRES:
NA.47

product name

7-Benzyloxy-4-trifluoromethylcoumarin, ≥99% (HPLC), solid

Livello qualitativo

Saggio

≥99% (HPLC)

Forma fisica

solid

Temperatura di conservazione

−20°C

Stringa SMILE

FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12

InChI

1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2
WVKLERKKJXUPIK-UHFFFAOYSA-N

Informazioni sul gene

Applicazioni

7-Benzyloxy-4-trifluoromethylcoumarin has been used:

  • in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
  • in O-dealkylation reaction to determine the activity of CYP3A
  • to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)

Azioni biochim/fisiol

Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.

Note legali

Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


Certificati d'analisi (COA)

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