Passa al contenuto
Merck

Vai a

A9899

Antazoline hydrochloride

Sinonimo/i:

2-(N-Benzylanilinomethyl)-2-imidazoline hydrochloride

Autenticati per visualizzare i prezzi organizzativi e contrattuali.

Informazioni su questo articolo

Formula empirica (notazione di Hill):
C17H19N3 · HCl
Numero CAS:
Peso molecolare:
301.81
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
219-719-8
MDL number:
Form:
powder
Quality level:


form

powder

Quality Level

originator

Novartis

SMILES string

Cl.C1CN=C(CN(Cc2ccccc2)c3ccccc3)N1

InChI

1S/C17H19N3.ClH/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;/h1-10H,11-14H2,(H,18,19);1H

InChI key

SWKDMSRRIBZZAY-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

Biochem/physiol Actions

Imidazoline agonist; H1 histamine receptor antagonist.
Imidazoline agonist; more potent than efaroxan in inducing insulin release from β cells; H1 histamine receptor antagonist.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Confronta articoli simili

Visualizza il confronto per intero

Mostra le differenze

1 of 1

Questo articolo
D3630A1210000N5504
Antazoline hydrochloride European Pharmacopoeia (EP) Reference Standard

A1210000

Antazoline hydrochloride

form

powder

form

powder

form

-

form

powder

Quality Level

200

Quality Level

200

Quality Level

-

Quality Level

100

originator

Novartis

originator

Johnson & Johnson

originator

-

originator

Allergan

Gene Information

human ... HRH1(3269)

Gene Information

human ... HRH1(3269)

Gene Information

human ... HRH1(3269)

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)


Still not finding the right product?

Explore all of our products under


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti



Chesley J Christensen et al.
Behavioral neuroscience, 123(1), 165-171 (2009-01-28)
Fischer and Lewis rat strains often serve as animal vulnerability models for drug abuse and addiction. When these strains respond for drugs of abuse, several measures, including total drug intake, response rate and progressive-ratio breakpoints, have been reported to be
M Mourtada et al.
Naunyn-Schmiedeberg's archives of pharmacology, 361(2), 146-154 (2000-02-24)
Pancreatic beta-cells express imidazoline binding sites which play a role in the regulation of insulin secretion, but it is not known whether ligands for these sites also affect other aspects of beta-cell physiology. In the present study, we have investigated
D Berdeu et al.
European journal of pharmacology, 254(1-2), 119-125 (1994-03-11)
The effects of imidazolines and derivatives were studied on insulin secretion and vascular resistance in the isolated perfused rat pancreas. On insulin secretion, two imidazoline alpha 2-adrenoceptor antagonists, efaroxan (1-100 microM) and RX821002 (10 microM), had a stimulating response; however



Numero articolo commerciale globale

SKUGTIN
A9899-25G04061832088778

Domande

Recensioni

Nessuna valutazione

Filtri attivi