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Merck
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Documenti

A126

Sigma-Aldrich

(±)-HA-966

Sinonimo/i:

(±)-3-Amino-1-hydroxy-2-pyrrolidone

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About This Item

Formula empirica (notazione di Hill):
C4H8N2O2
Numero CAS:
Peso molecolare:
116.12
Numero MDL:
Codice UNSPSC:
12352200
ID PubChem:

Stringa SMILE

NC1CCN(O)C1=O

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Valéria Martinez et al.
Pain, 99(3), 537-545 (2002-10-31)
Systemic opioid dosing until adequate analgesia in neuropathic pain may involve intolerable and untreatable side effects. Peripheral opioid receptor mechanisms may participate in the antinociceptive effect of systemic morphine. We evaluated the effect of peripherally injected morphine alone, and the
Joanne E Nash et al.
Movement disorders : official journal of the Movement Disorder Society, 17(3), 455-466 (2002-07-12)
Treatments for Parkinson's disease based on replacement of lost dopamine have several problems. Following loss of dopamine, enhanced N-methyl-D-aspartate (NMDA) receptor-mediated transmission in the striatum is thought to be part of the cascade of events leading to the generation of
J Klein et al.
Pharmacopsychiatry, 36 Suppl 1, S78-S83 (2003-09-18)
We have previously shown that hypoxia and N-methyl-D-aspartate (NMDA) receptor activation induce breakdown of choline-containing phospholipids in rat hippocampus, a process which is mediated by calcium influx and phospholipase A (2) activation. Bilobalide, a constituent of Ginkgo biloba, inhibited this
Frédéric Adam et al.
Neuropharmacology, 51(2), 191-202 (2006-05-23)
N-methyl-D-aspartate (NMDA) receptors are widely involved in opioid tolerance. However, it is less clear whether NMDA receptor antagonists reverse already-established tolerance and whether the intensity of the nociceptive stimulus influences morphine tolerance. Three days after implantation of morphine or control
David L Walker et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(6), 2343-2351 (2002-03-16)
NMDA receptor antagonists block conditioned fear extinction when injected systemically and also when infused directly into the amygdala. Here we evaluate the ability of D-cycloserine (DCS), a partial agonist at the strychnine-insensitive glycine-recognition site on the NMDA receptor complex, to

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