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Merck
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Documenti

89822

Sigma-Aldrich

N-Arachidoyl-D-sphingosine

≥98.0% (TLC)

Sinonimo/i:

Cer(d18:1/20:0), (2S,3R,4E)-2-(Eicosanoylamino)-4-octadecene-1,3-diol, N-Arachidoyl-D-erythro-sphingosine, N-Eicosanoyl-D-sphingosine, N-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]eicosanamide, C20 Ceramide (d18:1/20:0), C20-Ceramide

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About This Item

Formula empirica (notazione di Hill):
C38H75NO3
Numero CAS:
7344-02-7
Peso molecolare:
594.01
Beilstein:
7316231
Numero MDL:
MFCD02259131
Codice UNSPSC:
12352211
ID PubChem:
329769547
NACRES:
NA.85

Saggio

≥98.0% (TLC)

Forma fisica

powder

Composizione

carbon content, 76.84%
hydrogen content, 12.73%
nitrogen content, 2.36%

Tipo di lipide

sphingolipids

Temperatura di conservazione

−20°C

Stringa SMILE

OC[C@]([H])(NC(CCCCCCCCCCCCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C38H75NO3/c1-3-5-7-9-11-13-15-17-18-19-20-22-24-26-28-30-32-34-38(42)39-36(35-40)37(41)33-31-29-27-25-23-21-16-14-12-10-8-6-4-2/h31,33,36-37,40-41H,3-30,32,34-35H2,1-2H3,(H,39,42)/b33-31+/t36-,37+/m0/s1
XWBWIAOWSABHFI-NUKVNZTCSA-N

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Codice della classe di stoccaggio

13 - Non Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Kumi Izawa et al.
Scientific reports, 7(1), 4298-4298 (2017-06-29)
Sepsis is a serious clinical problem. Negative regulation of innate immunity is associated with sepsis progression, but the underlying mechanisms remains unclear. Here we show that the receptor CD300f promotes disease progression in sepsis. CD300f
Thomas Morville et al.
Medicine and science in sports and exercise, 49(2), 308-316 (2016-09-30)
Fat metabolism and muscle adaptation was investigated in six older trained men (age, 61 ± 4 yr; V˙O2max, 48 ± 2 mL·kg·min) after repeated prolonged exercise). A distance of 2706 km (1681 miles) cycling was performed over 14 d, and
J Jiang et al.
Toxicology and applied pharmacology, 332, 100-108 (2017-07-25)
The mechanisms of idiosyncratic drug-induced hepatotoxicity remain largely unclear. It has demonstrated that the drug idiosyncrasy is potentiated in the context of inflammation and intracellular ceramides may play a role in this process. To study the mechanisms, HepG2 cells were
Wendi Teng et al.
Nutrients, 11(5) (2019-05-30)
Sulforaphane (SFA), a naturally active isothiocyanate compound from cruciferous vegetables used in clinical trials for cancer treatment, was found to possess potency to alleviate insulin resistance. But its underlying molecular mechanisms are still incompletely understood. In this study, we assessed
Baharan Fekry et al.
Nature communications, 9(1), 4149-4149 (2018-10-10)
Ceramides are important participants of signal transduction, regulating fundamental cellular processes. Here we report the mechanism for activation of p53 tumor suppressor by C16-ceramide. C16-ceramide tightly binds within the p53 DNA-binding domain (Kd ~ 60 nM), in close vicinity to the Box V

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