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73353

Atto 647N iodoacetamide

BioReagent, suitable for fluorescence

Autenticati per visualizzare i prezzi organizzativi e contrattuali.

Informazioni su questo articolo

UNSPSC Code:
12352200


product line

BioReagent

form

solid

mol wt

Mw 969 g/mol

manufacturer/tradename

ATTO-TEC GmbH

fluorescence

λex 644 nm; λem 661 nm

suitability

suitable for fluorescence

storage temp.

−20°C

General description

Atto 647N is a superior label with high molecular absorption (150.000) and quantum yield (0.65) as well as sufficient stoke′s shift. Atto 647 N is characterized by a high thermal and photostability.
Absorption and fluorescence are independent of pH, at least in the most relevant range of pH 4 to 11. The iodoacetamide derivative reacts, like the maleimide, with a sulfhydryl group forming a thioether bond. It is predominantly used for tagging cystein residues of proteins.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.


Classe di stoccaggio

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Christian Eggeling et al.
Nature, 457(7233), 1159-1162 (2008-12-23)
Cholesterol-mediated lipid interactions are thought to have a functional role in many membrane-associated processes such as signalling events. Although several experiments indicate their existence, lipid nanodomains ('rafts') remain controversial owing to the lack of suitable detection techniques in living cells.
Feng Ye et al.
The Journal of endocrinology, 206(1), 27-36 (2010-04-16)
Adipose tissue is a highly active endocrine organ secreting a variety of signaling molecules called adipokines. Leptin and resistin are two adipokines critically involved in metabolic homeostasis. Nevertheless, the secretory pathways of these adipokines and their interplays are poorly elucidated.
Mengjun Xue et al.
Langmuir : the ACS journal of surfaces and colloids, 28(50), 17578-17584 (2012-11-24)
Mesoporous silica nanoparticles show promise as a drug-carrier vehicle for biomedical applications, but the development of simple, biocompatible capping systems has remained a challenge. We have found that lysozyme molecules can act as a pH-responsive nanovalve to block and unlock



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