Passa al contenuto
Merck
Tutte le immagini(1)

Documenti fondamentali

51290

Sigma-Aldrich

Hemoglobin from bovine blood

lyophilized, 2×cryst., ≥90% (SDS-PAGE), powder

Sinonimo/i:

Bovine hemoglobin, Hb, Methemoglobin

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(1)

About This Item

Numero CAS:
9008-02-0
Numero MDL:
MFCD00131282
Codice UNSPSC:
12352202

Origine biologica

bovine blood

Saggio

≥90% (SDS-PAGE)

Stato

powder

Qualità

2×cryst.
lyophilized

PM

Mr ~64500

tecniche

UV/Vis spectroscopy: suitable

Impurezze

salt, none detected
~0.3% Fe

Perdita

≤8% loss on drying

N° accesso UniProt

P01966
P02070
P02081
P06642
P06643

Temperatura di conservazione

2-8°C

Informazioni sul gene

cow ... HBA1(281221) , HBB(280813) , HBE2(513240) , HBE4(513108) , HBG(511735) , alpha globin(512439)

Cerchi prodotti simili? Visita Guida al confronto tra prodotti

Descrizione generale

Hemoglobin (Hb) is the protein responsible for storage and transport of oxygen and other gaseous ligands in red blood cells (RBC). Hb is also the pioneer material for synthesis of Hb-based oxygen carriers (HBOCs) that can be used as substitutes for RBC.

Applicazioni

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Azioni biochim/fisiol

Oxygen transporter, NO scavenger
Oxygen transporter. The Fe2+/Fe3+ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Avvertenza

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Altre note

Review: Oxygen carrier proteins
Sales restrictions may apply

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Scegli una delle versioni più recenti:

Certificati d'analisi (COA)

Lot/Batch Number
STBC9802V
STBC6994V
STBB5218V
STBB5218
STBB2081

Non trovi la versione di tuo interesse?

Se hai bisogno di una versione specifica, puoi cercare il certificato tramite il numero di lotto.

Cerca un COA

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Paul W Buehler et al.
Biomaterials, 31(13), 3723-3735 (2010-02-13)
Hemoglobin-based oxygen carriers (HBOC) are currently being developed as red blood cell (RBC) substitutes for use in transfusion medicine. Despite significant commercial development, late stage clinical results of polymerized hemoglobin (PolyHb) solutions hamper development. We synthesized two types of PolyHbs
M. Brunori et al.
Topics in Molecular and Structural Biology, 7, 263-263 (1985)
J L Schei et al.
Neuroscience, 227, 191-200 (2012-10-09)
Coupling between neural activity and hemodynamic responses is important in understanding brain function, interpreting brain-imaging signals, and assessing pathological conditions. Tissue state is a major factor in neurovascular coupling and may alter the relationship between neural and hemodynamic activity. However
Kaori Yamazaki et al.
Clinical physiology and functional imaging, 33(2), 109-116 (2013-02-07)
Time-resolved spectroscopy (TRS-20) measures tissue oxygen saturation (%) by evaluating the absolute concentrations of oxygenated, deoxygenated and total haemoglobin based on measurement of the transit time of individual photons through a tissue of interest. We measured tissue oxygen saturation in
Dafna Ben Bashat et al.
PloS one, 7(11), e49416-e49416 (2012-12-05)
Blood oxygenation level dependence (BOLD) imaging under either hypercapnia or hyperoxia has been used to study neuronal activation and for assessment of various brain pathologies. We evaluated the benefit of a combined protocol of BOLD imaging during both hyperoxic and
Visualizza tutti i documenti correlati

Chromatograms

application for HPLC

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.