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68069

Hippuric acid

analytical standard

Sinonimo/i:

N-Benzoylglycine, Benzoylaminoacetic acid

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50 mg

Disponibile per la spedizione OGGIdaSchnelldorf Distribution

198,00 €

Informazioni su questo articolo

Formula condensata:
C6H5CONHCH2COOH
Numero CAS:
Peso molecolare:
179.17
EC Number:
207-806-3
UNSPSC Code:
41116107
NACRES:
NA.24
Beilstein/REAXYS Number:
1073987
MDL number:

198,00 €


Disponibile per la spedizione OGGIDettagli


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grade

analytical standard

Quality Segment

assay

≥97.5% (GC)

shelf life

limited shelf life, expiry date on the label

mp

187-191 °C (lit.)

application(s)

clinical testing

format

neat

SMILES string

OC(=O)CNC(=O)c1ccccc1

InChI

1S/C9H9NO3/c11-8(12)6-10-9(13)7-4-2-1-3-5-7/h1-5H,6H2,(H,10,13)(H,11,12)

InChI key

QIAFMBKCNZACKA-UHFFFAOYSA-N

General description

Hippuric acid, the glycine conjugate of benzoic acid, is formed via a biotransformation process. From scientific literature, it is reported to be found as an excretory product in urine. Hippuric acid is also known to be catabolically synthesized from benzene-type aromatic compounds, believed to be originated from various factors such as environmental exposures, basic human liver metabolism of protein catabolism, cyclic sugar type-compounds, quinic acid, etc.[1]

Application

Hippuric acid may be used as an analytical reference standard for the quantification of the analyte in the following:
  • Human biological fluids using high-performance liquid chromatography (HPLC) with UV detection.
  • Human and rat urine samples using gas chromatography–mass spectrometry (GC–MS).
  • Human urine samples using GC equipped with a flame ionization detector.[2]

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Questo articolo
112003H93808.20649
Hippuric acid analytical standard

Supelco

68069

Hippuric acid

Hippuric acid 98%

Sigma-Aldrich

112003

Hippuric acid

Hippuric acid for synthesis

Sigma-Aldrich

8.20649

Hippuric acid

format

neat

format

-

format

-

format

-

grade

analytical standard

grade

-

grade

-

grade

-

mp

187-191 °C (lit.)

mp

187-191 °C (lit.)

mp

-

mp

188-190 °C

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

application(s)

clinical testing

application(s)

peptide synthesis

application(s)

detection

application(s)

-

assay

≥97.5% (GC)

assay

98%

assay

≥99%

assay

≥97.5% (acidimetric)


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Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Determination of benzoic acid and hippuric acid in human plasma and urine by high-performance liquid chromatography
Kubota K, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 425, 67-75 (1988)
Simultaneous determination of urinary hippuric acid, o-, m-and p-methylhippuric acids, mandelic acid and phenylglyoxylic acid for biomonitoring of volatile organic compounds by gas chromatography-mass spectrometry.
Ohashi Y, et al.
Analytica Chimica Acta, 566(2), 167-171 (2006)
Ronald W Pero
Current clinical pharmacology, 5(1), 67-73 (2009-11-07)
Hippuric acid has been a major human metabolite for years. However, there is no well-known documented health benefit associated with it except for excretion of environmental-toxic exposures of aromatic compounds such as toluene, or from dietary protein degradation and re-synthesis



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