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481981

Nifedipine

≥98% (UV), L-type Ca2+ channel bocker, solid

Sinonimo/i:

Nifedipine, L-Type Calcium Channel Blocker III

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Informazioni su questo articolo

Formula empirica (notazione di Hill):
C17H18N2O6
Numero CAS:
Peso molecolare:
346.33
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (UV)
Form:
solid
Quality level:
Storage condition:
OK to freeze, protect from light
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Nome del prodotto

Nifedipine, Relatively selective blocker of L-type Ca2+ channels.

description

Merck USA index - 14, 6528

Quality Level

assay

≥98% (UV)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, protect from light

color

yellow

solubility

DMSO: soluble, ethanol: soluble

shipped in

ambient

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Questo articolo
N0750000PHR1290BP462
Nifedipine Relatively selective blocker of L-type Ca2+ channels.

Sigma-Aldrich

481981

Nifedipine

Nifedipine European Pharmacopoeia (EP) Reference Standard

N0750000

Nifedipine

Nifedipine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1290

Nifedipine

Nifedipine British Pharmacopoeia (BP) Reference Standard

BP462

Nifedipine

manufacturer/tradename

Calbiochem®

manufacturer/tradename

EDQM

manufacturer/tradename

-

manufacturer/tradename

BP

form

solid

form

-

form

-

form

solid

assay

≥98% (UV)

assay

-

assay

-

assay

-

Quality Level

100

Quality Level

-

Quality Level

300

Quality Level

-

storage condition

OK to freeze, protect from light

storage condition

-

storage condition

-

storage condition

-

storage temp.

10-30°C

storage temp.

-

storage temp.

2-30°C

storage temp.

2-8°C

General description

Relatively selective blocker of L-type Ca2+ channels. One of the most extensively studied blockers of 1,4-dihydropyridine-type Ca2+ channels, and a pharmacologically-useful vasodilator. Induces apoptosis in human glioblastoma cells.

Biochem/physiol Actions

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
L-type Ca2+ channels

Preparation Note

Following reconstitution, refrigerate (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Reid, K., et al. 1997. J. Pharmacol. Exp. Ther. 283, 993.
Kondo, S., et al. 1995. J. Neurosurg.82, 469.
Antkiewicz-Michaluk, L., et al. 1994. Eur. J. Pharmacol. 254, 9.
Calabresi, P., et al. 1994. J. Neurosci. 14, 4871.
Akman, M.S., et al. 1993. Endocrinology132, 1286.
Cirillo, M., et al. 1993. Circ. Res.72, 847.
Young, R.J., et al. 1993. Biochim. Biophys. Acta1146, 81.
Janis, R., et al. 1987. Adv. Drug Res.16, 311.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificati d'analisi (COA)

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Numero articolo commerciale globale

SKUGTIN
481981-250MG04055977183443

Domande

  1. Could you please provide the upper limit of saturation in DMSO for item 481981, Nifedipine?

    1 risposta
    1. The highest test point found is that the substance is soluble in DMSO at a concentration of 50 mg/ml.

      Utile?

Recensioni

Nessuna valutazione

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