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Merck
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Documenti

07-580

Sigma-Aldrich

Anti-IKKε Antibody

Upstate®, from rabbit

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100

Forma dell’anticorpo

purified antibody

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Reattività contro le specie

human, mouse

Produttore/marchio commerciale

Upstate®

tecniche

western blot: suitable

Isotipo

IgG

N° accesso NCBI

NM_014002

N° accesso UniProt

Q14164

Condizioni di spedizione

wet ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... IKBKE(9641)
mouse ... Ikbke(56489)

Specificità

IKKε

Immunogeno

KLH-conjugated, synthetic peptide corresponding to amino acids 582-596 (SHLAKRLLQVFQEEC) of human IKKε

Applicazioni

Research Category
Signaling
Research Sub Category
Immunological Signaling
This Anti-IKKε Antibody is validated for use in WB for the detection of IKKε.

Descrizione del bersaglio

Mr 80kDa

Stato fisico

Format: Purified
Protein A purified
of 0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%

Stoccaggio e stabilità

Stable for 2 years at -20°

Note legali

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Certificati d'analisi (COA)

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Vladimir V Kravchenko et al.
The Journal of biological chemistry, 278(29), 26612-26619 (2003-05-09)
We report that the product of the inducible gene encoding the kinase known as IKKi/IKKepsilon (IKKi) is required for expression of a group of genes up-regulated by pro-inflammatory stimuli such as bacterial endotoxin (lipopolysaccharide (LPS)). Here, using murine embryonic fibroblasts
Lídia Hernandez et al.
Cancer research, 70(10), 4005-4014 (2010-04-29)
The NF-kappaB family of transcription factors has been implicated in the propagation of ovarian cancer, but the significance of constitutive NF-kappaB signaling in ovarian cancer is unknown. We hypothesized that constitutive NF-kappaB signaling defines a subset of ovarian cancer susceptible
Tina Ruggiero et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(9), 2898-2908 (2009-05-09)
The importance of post-transcriptional mechanisms for the regulation of the homoeostasis of the immune system and the response to challenge by microorganisms is becoming increasingly appreciated. We investigated the contribution of microRNAs (miRNAs) to macrophage activation induced by lipopolysaccharide (LPS).
Congwen Wei et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(5), E601-E610 (2014-01-23)
Resistance to antiestrogens is one of the major challenges in breast cancer treatment. Although phosphorylation of estrogen receptor α (ERα) is an important factor in endocrine resistance, the contributions of specific kinases in endocrine resistance are still not fully understood.

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

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