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06-207

Anti-Lyn Antibody

serum, Upstate®

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Taglio della confezioneSKUDisponibilitàPrezzo
250 μL

Spedizione prevista il03 giugno 2026daMerck S.p.A

368,00 €

Informazioni su questo articolo

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
17

368,00 €


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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... LYN(4067)

General description

53 and 56kDa

Immunogen

peptide (NKQQRPVPESQL-LPGQRFQT) corresponding to residues 39-58 of human Lyn

Application

Anti-Lyn Antibody detects level of Lyn & has been published & validated for use in IP & WB.

Biochem/physiol Actions

two known forms of human Lyn

Physical form

whole antiserum containing 0.05% sodium azide

Analysis Note

Control
Positive Antigen Control: Catalog #12-301, non-stimulated A431 cell lysate. Add 2.5µL of 2-mercaptoethanol/100µL of lysate and boil for 5 minutes to reduce the preparation. Load 20µg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on RIPA lysates from human A431 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Questo articolo
SAB1410763SAB1406095AB4344
biological source

rabbit

biological source

rabbit

biological source

mouse

biological source

rabbit

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

antibody form

serum

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

species reactivity

human

species reactivity

mouse, human

species reactivity

human

species reactivity

mouse

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

western blot: 1 μg/mL

technique(s)

indirect immunofluorescence: suitable, western blot: 1 μg/mL

technique(s)

western blot: suitable


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Classe di stoccaggio

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificati d'analisi (COA)

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B M Vonakis et al.
The Journal of biological chemistry, 272(38), 24072-24080 (1997-09-20)
Aggregation of the high affinity receptor for IgE (FcepsilonRI) leads to the phosphorylation of tyrosines on the beta and gamma chains of the receptor by the Src family kinase Lyn. We have studied the interaction between Lyn and the FcepsilonRI
Genetic evidence for a tyrosine kinase cascade preceding the mitogen-activated protein kinase cascade in vertebrate G protein signaling
Wan, Y., et al
The Journal of Biological Chemistry, 272, 17209-17215 (1997)
M E Bates et al.
American journal of respiratory cell and molecular biology, 18(1), 75-83 (1998-02-03)
Eosinophils are potent effector cells contributing to allergic inflammation and asthma. The differentiation, recruitment, and effector functions of eosinophils are greatly affected by interleukin (IL)-5. In the eosinophil, signal transduction pathways including Jak-STAT and Ras-Raf-MAP kinase are stimulated by IL-5



Numero articolo commerciale globale

SKUGTIN
06-20704053252589003

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