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04-469

Anti-SREBP1 Antibody, clone 2121

clone 2121, Upstate®, from mouse

Sinonimo/i:

SREBF1, sterol regulatory element binding transcription factor 1

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Taglio della confezioneSKUDisponibilitàPrezzo
25 μL

Spedizione prevista il05 maggio 2026daMerck S.p.A

156,00 €
100 μL

Spedizione prevista il07 maggio 2026daMerck S.p.A

398,00 €

Informazioni su questo articolo

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
2121, monoclonal
Application:
WB
Citations:
12

156,00 €


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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

2121, monoclonal

species reactivity

human

packaging

antibody small pack of 25 μL

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SREBF1(6720)

General description

126 kDa

Immunogen

Recombinant His-tagged human SREBP-1a protein encompassing amino acids 301-407.

Application

Anti-SREBP1 Antibody, clone 2121 is a Mouse Monoclonal Antibody for detection of SREBP1 also known as sterol regulatory element binding transcription factor 1 & has been validated in WB.

Biochem/physiol Actions

Reacts with the basic helix-loop-helix leucine zipper (bHLH-ZIP) of SREBP.

Physical form

100 μL (1 mg/mL) of protein A purified mouse monoclonal IgG1 in PBS with 0.1% sodium azide.
Format: Purified

Preparation Note

Stable for 2 years at -20°C from date of shipment. Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol-containing solutions to become frozen during storage.

Analysis Note

Routinely evaluated by immunoblot.

Other Notes

Please refer to lot specific datasheet.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

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Questo articolo
MABS2034ABS1508MABS1988
Anti-SREBP-1 from rabbit, purified by affinity chromatography

Sigma-Aldrich

ABS1508

Anti-SREBP-1

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

biological source

mouse

biological source

mouse

biological source

rabbit

biological source

rabbit

clone

2121, monoclonal

clone

2A4, monoclonal

clone

polyclonal

clone

22D5, monoclonal

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

unpurified

species reactivity

human

species reactivity

hamster, canine, human

species reactivity

human

species reactivity

mouse, human

shipped in

dry ice

shipped in

-

shipped in

ambient

shipped in

ambient


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Classe di stoccaggio

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Tanel Punga et al.
The Journal of biological chemistry, 281(35), 25278-25286 (2006-07-11)
Members of the sterol regulatory element-binding protein (SREBP) family of transcription factors control cholesterol and lipid metabolism and play critical roles during adipocyte differentiation. The transcription factor SREBP1 is degraded by the ubiquitin-proteasome system following phosphorylation of Thr426 and Ser430
Shreetama Bandyopadhayaya et al.
Journal of biochemical and molecular toxicology, 35(4), e22693-e22693 (2021-01-05)
N-acyl dopamines (NADAs) are bioactive lipids of the endovanilloid family with known cytotoxicity for the cancer cells; however, the available data on the participation of the endovanilloids in epithelial-mesenchymal transition (EMT) and cancer stemness are controversial. This study unveils the
Amy K Walker et al.
Genes & development, 24(13), 1403-1417 (2010-07-03)
The sterol regulatory element-binding protein (SREBP) transcription factor family is a critical regulator of lipid and sterol homeostasis in eukaryotes. In mammals, SREBPs are highly active in the fed state to promote the expression of lipogenic and cholesterogenic genes and



Numero articolo commerciale globale

SKUGTIN
04-469-25UL04054839350122

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