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SAB3500326

Anti-PKR antibody produced in rabbit

Name: Anti-PKR antibody produced in rabbit
Brand: SIGMA
Price: 498 EUR

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-Interferon-inducible RNA-dependent protein kinase, Anti-Protein kinase RNA-activated

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Taglio della confezione	SKU	Disponibilità	Prezzo
100 μg		Per informazioni sulla disponibilità, contatta il Servizio Clienti.	498,00 €

Informazioni su questo articolo

UNSPSC Code:

12352203

NACRES:

NA.41

MDL number:

MFCD03455796

Conjugate:

unconjugated

Clone:

polyclonal

Application:

ELISA (i), IF, IHC, WB

Citations:

498,00 €

Per informazioni sulla disponibilità, contatta il Servizio Clienti.

Per il tuo target è disponibile un anticorpo ricombinante privo di conservanti. Prova ZRB1929

Servizio Tecnico

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Proprietà

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, mouse, rat

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

NCBI accession no.

AAP57628

UniProt accession no.

P19525

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EIF2AK2(5610)

Descrizione

General description

EIF2AK2 (eukaryotic translation initiation factor 2 α kinase 2) is an intracellular protein that is also called as RNA-dependent protein kinase (PKR). It belongs to the eIF2α family of protein kinases. The protein contains two RNA binding domains and a kinase domain. The PKR gene is localized on human chromosome 2p22-p21.

Immunogen

PKR antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human PKR.

Application

Anti-PKR antibody produced in rabbit has been used in Western Blotting.

Biochem/physiol Actions

EIF2AK2 (eukaryotic translation initiation factor 2 α kinase 2) plays a key role in antiviral responses promoted by interferons. It is involved in stress response and inflammation pathways. EIF2AK2 controls the development and multiplication of cells, nutrient signaling and metabolism. The protein also participates in several cell regulatory pathways like antiviral activity, growth suppression, transcriptional regulation and apoptosis.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied in PBS with 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500326.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Questo articolo	SAB4504517	SAB4300533	P0244
Sigma-Aldrich SAB3500326 Anti-PKR antibody produced in rabbit	Sigma-Aldrich SAB4504517 Anti-phospho-PKR (pThr⁴⁴⁶) antibody produced in rabbit	Sigma-Aldrich SAB4300533 Anti-EIF2AK2 (Ab-451) antibody produced in rabbit	$Anti-PKR (ET-20) antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution$ Sigma-Aldrich P0244 Anti-PKR (ET-20) antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level -	Quality Level 200
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form IgG fraction of antiserum
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
Gene Information human ... EIF2AK2(5610)	Gene Information human ... EIF2AK2(5610)	Gene Information human ... EIF2AK2(5610)	Gene Information human ... EIF2AK2(5610)

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Classe di stoccaggio

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

39470602

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Polymorphism in the NLRP3 inflammasome-associated EIF2AK2 gene and inflammatory bowel disease

Geena Paramel Varghese

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Numero articolo commerciale globale

SKU	GTIN
SBP3500326-0.05MG	04061832161037
SAB3500326-100UG	04061832495484

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Recensioni

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