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D4001

Sigma-Aldrich

2′-Deoxyuridine 5′-triphosphate sodium salt

≥95%

Sinonimo/i:

dUTP sodium salt

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About This Item

Formula empirica (notazione di Hill):
C9H15N2O14P3 · xNa+
Numero CAS:
102814-08-4
Peso molecolare:
468.14 (free acid basis)
Numero MDL:
MFCD00084701
Codice UNSPSC:
41106305
ID PubChem:
24893804
NACRES:
NA.51

Origine biologica

synthetic (organic)

Saggio

≥95%

Forma fisica

powder

Temperatura di conservazione

−20°C

Stringa SMILE

[Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=CC(=O)NC2=O

InChI

1S/C9H15N2O14P3.Na.H/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;
FVFWWPFKJNTHIQ-UHFFFAOYSA-N

Applicazioni

2′-Deoxyuridine 5′-triphosphate (dUTP) may be used to study the distribution, specificity and kinetics of deoxyuridine 5′-triphosphate nucleotidohydrolase(s) (dUTPase, EC 3.6.1.23). dUTPase are important enzymes that protect cells from the incorporation of dUTP into DNA.dUTP is a component of the TUNEL (terminal deoxyribonucleotidyl-transferase-(TdT)-mediated deoxyuridine-5′-triphosphate- (dUTP) nick-end labeling) test. TUNEL is a common method for detecting DNA fragmentation that results from apoptotic signaling cascades.
2′-Deoxyuridine 5′-triphosphate sodium salt has been used in the extraction of white muscles from the African catfish.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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2′-Deoxycytidine ≥99% (HPLC)

Sigma-Aldrich

D3897

2′-Deoxycytidine

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Previous studies have indicated that improper use of mitomycin C (MMC) caused cytotoxicity in corneal endothelial cells. The aim of the present study was to investigate whether MMC induces cellular apoptosis in corneal endothelial cells and to determine the mechanism
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Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 26(6), 1011-1022 (2011-01-12)
Myocardium is very sensitive to gravitational changes. During a spaceflight cardiovascular atrophy paired with rhythm problems and orthostatic intolerance can occur. The aim of this study was to investigate the impact of basic fibroblast growth factor (bFGF) and vascular endothelial
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To evaluate apoptosis and cell proliferation on cytologic specimens (smears) from endoscopic retrograde cholangiopancreatography in patients with ampulary carcinoma and to correlate that relationship with the grade of the tumors. Forty patients (23 males and 17 females) aged 45-81 who
Lucy Freeman et al.
The Journal of biological chemistry, 284(37), 25280-25289 (2009-07-10)
Deoxyuridine 5'-triphosphate pyrophosphatases (dUTPases) are ubiquitous enzymes essential for hydrolysis of dUTP, thus preventing its incorporation into DNA. Although Epstein-Barr virus (EBV) dUTPase is monomeric, it has a high degree of similarity with the more frequent trimeric form of the
Dietary canitine maintains energy reserves and delays fatigue of exercised african catfish (Clarias gariepinus) fed high fat diets
Ozorio R, et al.
Scientia Agricola, 62(3), 208-213 (2005)
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