Glicoconiugati
I glicoconiugati sono molecole composte da un carboidrato, o glicano, legato in maniera covalente a una proteina, un lipide, un peptide o ad altro composto. I glicoconiugati si formano per glicosilazione e sono coinvolti in svariati processi biologici all’interno degli organismi. Nell’ambito della glicobiologia, la ricerca si occupa di studiare la struttura e l’attività dei carboidrati e dei glicoconiugati in rapporto alla salute umana. La comprensione di come le alterazioni dei processi glicobiologici possano condurre a patologie gravi è di notevole importanza anche in biologia molecolare, in biologia cellulare, in proteomica e in medicina.
Proponiamo un portfolio di glicoconiugati completo, comprensivo di glicolipidi, glicoproteine e lipopolisaccaridi per qualsiasi esigenza di ricerca, ivi incluse l’estrazione, la caratterizzazione, la formulazione e le modificazioni chimiche/enzimatiche che contemplino il ricorso a condizioni di reazione o modi di attivazione non convenzionali. Potrete: scoprire di nuovi target farmaceutici per patologie infettive, infiammatorie o oncologiche; sviluppare nuovi possibili vaccini per il cancro, le infezioni virali o batteriche e altre patologie; esplorare altre applicazioni potenziali dei glicoconiugati come agenti terapeutici.
Risorse correlate
- Article: BIOshell Glycan HPLC Columns
Fast, high-resolution separations of procainamide labeled glycans - dextran ladder, human IgG and cetuximab
- Article: Deglycosylation Kits
Find deglycosylation kits for your research. Review the different features of deglycosylation kits for glycoproteins, enzymatic proteins, and native proteins.
- Article: Enzymatic Deglycosylation
Enzymatic Deglycosylation Strategies: Sequential hydrolysis of individual monosaccharides from glycans can be useful for the elucidation of the structure and function of the glycan component.
- Article: Glycoprotein Deglycosylation
Information about Glycoprotein deglycosylation. The diversity of oligosaccharide structures, both O-linked and N-linked, often results in heterogeneity in the mass and charge of glycoproteins.
- Article: Glycosaminoglycans and Proteoglycans
Uncover more about glycosaminoglycans and proteoglycans including the structure of glycosaminoglycans (GAGs), the different types of GAGs, and their functions.
- Article: Glycosphingolipids
Glycosphingolipids
- Article: GPI Anchored Glycoproteins
GPI Anchored Glycoproteins
- Article: Lipopolysacharides
Lipopolysaccharide (LPS) is a major component of Gram-negative bacteria, important for microbiological research.
- Article: Peptidoglycans
Peptidoglycan structure: alternating GlcNAc and N-acetylmuramic acid cross-linked to peptides form the basic backbone.
- Article: Purification and Removal of Glycoproteins and Polysaccharides
- Article: Strategies for Deglycosylating N-linked Glycans
Explore strategies for releasing N-linked glycans with PNGase F, PNGase A & native & sequential deglycosylation with endoglycosidases & exoglycosidases.
- Brochure: Glycobiology
Glycobiology and glycoproteomics are crucial in life science, with diverse glycoproteins and important roles in cellular communication and physiology.
- Brochure: Glycoconjugates from GlycoNZ
Glycobiology is vital in understanding carbohydrates' role in human health. We offer a wide range of products, including glycoconjugates, and have expanded our portfolio through a partnership with GlycoNZ, offering more opportunities for exploring drug targets for various diseases.
- Selection Guide: Deglycosylation
Complete kits for highly specific deglycosylation.
- Selection Guide: Glycoproteomics Selection Guide — Deglycosylation
Glycoproteomics Selection Guide — Deglycosylation and Glycoproteomics Selection Guide — Labeling and Detection, Quantitation
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